The mechanistic influences of dopamine (DA) signaling and impact on motor function are
nearly always interpreted from changes in nigrostriatal neuron terminals in striatum. This is a …

Background The choroid plexus (CP) is involved in the clearance of harmful metabolites
from the brain, as a part of the glymphatic system. This study aimed to investigate the …

After contracting COVID-19, a substantial number of individuals develop a Post-COVID-
Condition, marked by neurologic symptoms such as cognitive deficits, olfactory dysfunction …

Background Multiple system atrophy (MSA) clinically manifests with either predominant
nigrostriatal or cerebellopontine degeneration. This corresponds to two different …

Objectives The precise segmentation of atrophic structures remains challenging in
neurodegenerative diseases. We determined the performance of a Deep Neural Patchwork …

Background Nigrostriatal microstructural integrity has been suggested as a biomarker for
levodopa response in Parkinson's disease (PD), which is a strong predictor for motor …

Purpose Various MRI-based techniques were tested for the differentiation of
neurodegenerative Parkinson syndromes (NPS); the value of these techniques in direct …

Thesis Summary Non-motor symptoms are a major component of Parkinson's Disease and
have a significant impact on quality of life. Outcome measures of pre-clinical studies …