[HTML][HTML] IgA nephropathy

JC Rodrigues, M Haas, HN Reich - Clinical Journal of the …, 2017 - journals.lww.com
IgA nephropathy (IgAN) is a leading cause of CKD and renal failure. Recent international
collaborative efforts have led to important discoveries that have improved our understanding …

IgA nephropathy

KN Lai, SCW Tang, FP Schena, J Novak… - Nature reviews Disease …, 2016 - nature.com
Abstract Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis
that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but …

[HTML][HTML] The origin and activities of IgA1-containing immune complexes in IgA nephropathy

B Knoppova, C Reily, N Maillard, DV Rizk… - Frontiers in …, 2016 - frontiersin.org
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, frequently leading
to end-stage renal disease, as there is no disease-specific therapy. IgAN is diagnosed from …

[HTML][HTML] Inhibition of STAT3 signaling reduces IgA1 autoantigen production in IgA nephropathy

K Yamada, ZQ Huang, M Raska, C Reily… - Kidney international …, 2017 - Elsevier
Introduction IgA nephropathy is a chronic renal disease characterized by mesangial
immunodeposits that contain autoantigen, which is aberrantly glycosylated IgA1 with some …

Immunoglobulin A nephropathy: advances in understanding of pathogenesis and treatment

RA Lafayette, E Kelepouris - American journal of nephrology, 2018 - karger.com
Background: Immunoglobulin A (IgA) nephropathy is the most common form of primary
glomerulonephritis and has clinical associations with a wide range of inflammatory and …

Long-term outcomes of patients with IgA nephropathy categorized by the International IgAN risk prediction tool and by the degree of hematuria at diagnosis

R Ebbestad, M Sanaei Nurmi, S Lundberg - Nephron, 2022 - karger.com
Abstract Introduction: Within 30 years, 20–50% of IgA nephropathy (IgAN) patients progress
to end-stage kidney disease (ESKD). Identifying these patients can be difficult since renal …

The association of microhematuria with mesangial hypercellularity, endocapillary hypercellularity, crescent score and renal outcomes in immunoglobulin A …

SA Bobart, MP Alexander, K Shawwa… - Nephrology Dialysis …, 2021 - academic.oup.com
Background Microhematuria is common in immunoglobulin A nephropathy (IgAN). However,
current prognostication is based on proteinuria and mesangial hypercellularity …

Hematuria was a high risk for renal progression and ESRD in immunoglobulin a nephropathy: a systematic review and meta-analysis

P He, H Wang, C Huang, L He - Renal Failure, 2021 - Taylor & Francis
Background: The relationship between hematuria, a typical presentation of immunoglobulin
A nephropathy (IgAN), and long-term adverse prognosis of these patients is still …

[HTML][HTML] Time-averaged hematuria as a prognostic indicator of renal outcome in patients with IgA nephropathy

M Weng, J Lin, Y Chen, X Zhang, Z Zou… - Journal of Clinical …, 2022 - mdpi.com
We aim to investigate the association of time-averaged hematuria (TA-hematuria) with the
progression of IgA nephropathy (IgAN). Based on TA-hematuria during follow-up, 152 …

[HTML][HTML] Proliferation and cytokine production of human mesangial cells stimulated by secretory IgA isolated from patients with IgA nephropathy

Y Liang, J Zhang, Y Zhou, G Xing, G Zhao… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: IgA nephropathy (IgAN) is the most common form of primary
glomerulonephritis, and often aggravates by mucosal infection. Secretory IgA (SIgA) is the …