Approximately a century ago, in 1916, the term 'hydrotropy'was coined by the scientist Carl
A. Neuberg to address anionic organic salts which considerably augmented the aqueous …

The hydrotropy though existing as precisely used scientific approach assisting solubilization
for all. It took 66 long years to use the concept in drug analysis since its inception in 1916 …

The aim of this work is to evaluate simple, sensitive, effective and validated procedures for
the determination of cefotaxime, cefoperazone, ceftazidime and cefadroxil. In this study, the …

Drug development plays an important role in patient safety and effectiveness. The
therapeutic suitability of a new drug depends on the solubility. The solubility of the sparingly …

In the present investigation, hydrotropic solution of urea was employed as a solubilizing
agent for spectrophotometric determination of poorly water-soluble drug rosiglitazone …

International Journal of Chemistry Research Page 1 Research Article DEVELOPMENT AND
VALIDATION OF A UV-VIS SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION AND …

The aim of present investigation is to establish simple and economical UV-
Spectrophotometric methods for estimation of Tolvaptan using Zero order UV …

In titrimetric analysis costlier organic solvents are more often employed to solubilize the
poorly water-soluble drugs. Volatility and pollution are drawbacks of such solvents. Various …

ABSTRACT A Simple, accurate and reproducible spectrophotometric method by
Hydrotrophic Solubilisation was developed for the estimation of Esomeprazole. In the …

Quantitative spectrophotometric analysis of poorly water-soluble drugs involves use of
various organic solvents. Major drawbacks of organic solvents include high cost, volatility …