An emerging strategy for synthesizing nanoclusters and nanoparticles involves the
confinement of particle precursors within small volumes and the subsequent reduction and …

Encapsulation of small molecule drugs in long‐circulating lipid nanoparticles (LNPs) can
reduce toxic side effects and enhance accumulation at tumor sites. A fundamental problem …

Liposomes have attracted much attention as the first nanoformulations entering the clinic.
The optimization of physicochemical properties of liposomes during nanomedicine …

Nanomedicines have gained much attention for the delivery of small molecules or nucleic
acids as treatment options for many diseases. However, the transfer from experimental …

Despite the outstanding progress in modern medicine, the oral delivery of peptide drugs is
limited until today due to their instability in the gastrointestinal tract and low mucosa …

Macrophage recognition of nanoparticles is highly influenced by particle size and surface
modification. Due to the lack of appropriate in vivo screening models, it is still challenging …

For more than 30 years, treatment of acute myeloid leukemia (AML) has remained largely
unchanged and reliant on chemotherapeutic drug combinations, specifically cytarabine and …

Active targeting and specific drug delivery to parenchymal liver cells is a promising strategy
to treat various liver disorders. Here, we modified synthetic lipid-based nanoparticles with …

Microfluidic flow focusing devices are widely used to generate steep chemical concentration
gradients at the interface between miscible or partially miscible streams. In this study, first we …

Cellular delivery of DNA vectors for the expression of therapeutic proteins is a promising
approach to treat monogenic disorders or cancer. Significant efforts in a preclinical and …