Recent human decedent model studies, and compassionate xenograft use have explored
the promise of porcine organs for human transplantation. To proceed to human studies, a …

Abstract Analysis of non‐Gal antibody induced after pig‐to‐baboon cardiac
xenotransplantation identified the glycan produced by porcine beta‐1, 4‐N‐acetyl …

The tetrasaccharide structures Siaα2, 3Galβ1, 3 (Fucα1, 4) GlcNAc and Siaα2, 3Galβ1, 4
(Fucα1, 3) GlcNAc constitute the epitopes of the carbohydrate antigens sialyl-Lewis a (sLea) …

Purified human mucins from different parts of the intestinal tract (ileum, cecum, transverse
and sigmoid colon and rectum) were isolated from two individuals with blood group ALeb (A …

Influenza A virus (IAV) is a pathogen that poses significant risks to human health. It is
therefore critical to develop strategies to prevent influenza disease. Many loss-of-function …

Copy number variants (CNVs) underlie many aspects of human phenotypic diversity and
provide the raw material for gene duplication and gene family expansion. However, our …

Background Xenograft rejection of pigs organs with an engineered mutation in the GGTA‐1
gene (GTKO) remains a predominantly antibody mediated process which is directed to a …

9Ortho-Clinical Diagnostics, Raritan, NJ, USA 10Drexel University College of Medicine,
Philadelphia, PA, USA 11Gamma Biologicals Inc (subsidiary of Immunocor Inc), Houston …

Uromodulin (UMOD) is a major risk gene for monogenic and complex forms of kidney
disease. The encoded kidney-specific protein uromodulin is highly abundant in urine and …

Prolific sheep have proven to be a valuable model to identify genes and mutations
implicated in female fertility. In the Lacaune sheep breed, large variation in litter size is …