This review is aimed at celebrating the upcoming 20th anniversary of the birth of human
functional near-infrared spectroscopy (fNIRS). After the discovery in 1992 that the functional …

This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Mapping of human brain function has revolutionized systems neuroscience. However,
traditional functional neuroimaging by positron emission tomography or functional magnetic …

Near-infrared spectroscopy (NIRS) is a noninvasive neuroimaging tool for studying evoked
hemodynamic changes within the brain. By this technique, changes in the optical absorption …

This review is aimed at presenting the state-of-the-art of time domain (TD) functional near-
infrared spectroscopy (fNIRS). We first introduce the physical principles, the basics of …

Time-correlated single photon counting (TCSPC) is based on the detection of single photons
of a periodic light signal, measurement of the detection time of the photons, and the build-up …

Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

We present three-dimensional (3D) in vivo images of human breast cancer based on
fluorescence diffuse optical tomography (FDOT). To our knowledge, this work represents the …

Near-infrared spectroscopy (NIRS) is an optical technique that can measure brain tissue
oxygenation and haemodynamics in real-time and at the patient bedside allowing medical …

Significance: Near-infrared spectroscopy (NIRS) combined with diffuse correlation
spectroscopy (DCS) provides a noninvasive approach for monitoring cerebral blood flow …