Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

More than 90% of the cell wall of the filamentous fungus Aspergillus fumigatus comprises
polysaccharides. Biosynthesis of the cell wall polysaccharides is under the control of three …

Deadly infections from opportunistic fungi have risen in frequency, largely because of the at-
risk immunocompromised population created by advances in modern medicine and the …

Fungal-mediated disease progression and antifungal drug efficacy are significantly
impacted by the dynamic infection microenvironment. At the site of infection, oxygen often …

The β-glucan receptor Dectin-1 is a member of the C-type lectin family and functions as an
innate pattern recognition receptor in antifungal immunity. In both mouse and man, Dectin-1 …

Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Microbial populations form intricate macroscopic colonies with diverse morphologies whose
functions remain to be fully understood. Despite fungal colonies isolated from environmental …

Aspergillus fumigatus is a mold that causes severe pulmonary infections. Our knowledge of
how A. fumigatus growth is controlled in the respiratory tract is developing, but still limited …

Pathogens hide immunogenic epitopes from the host to evade immunity, persist and cause
infection. The opportunistic human fungal pathogen Candida albicans, which can cause …

Previous work has shown that environmental and clinical isolates of Aspergillus fumigatus
represent a diverse population that occupies a variety of niches, has extensive genetic …