The genetics of human personality
Personality traits are the relatively enduring patterns of thoughts, feelings and behaviors that
reflect the tendency to respond in certain ways under certain circumstances. Twin and family …
reflect the tendency to respond in certain ways under certain circumstances. Twin and family …
Glypicans and heparan sulfate in synaptic development, neural plasticity, and neurological disorders
K Kamimura, N Maeda - Frontiers in neural circuits, 2021 - frontiersin.org
Heparan sulfate proteoglycans (HSPGs) are components of the cell surface and
extracellular matrix, which bear long polysaccharides called heparan sulfate (HS) attached …
extracellular matrix, which bear long polysaccharides called heparan sulfate (HS) attached …
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors
In the developing central nervous system (CNS), the control of synapse number and function
is critical to the formation of neural circuits. We previously demonstrated that astrocyte …
is critical to the formation of neural circuits. We previously demonstrated that astrocyte …
Heritability estimates of the Big Five personality traits based on common genetic variants
According to twin studies, the Big Five personality traits have substantial heritable
components explaining 40–60% of the variance, but identification of associated genetic …
components explaining 40–60% of the variance, but identification of associated genetic …
Astrocyte-secreted glypican 4 regulates release of neuronal pentraxin 1 from axons to induce functional synapse formation
I Farhy-Tselnicker, ACM van Casteren, A Lee… - Neuron, 2017 - cell.com
The generation of precise synaptic connections between developing neurons is critical to
the formation of functional neural circuits. Astrocyte-secreted glypican 4 induces formation of …
the formation of functional neural circuits. Astrocyte-secreted glypican 4 induces formation of …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Intergenerational neural mediators of early-life anxious temperament
Understanding the heritability of neural systems linked to psychopathology is not sufficient to
implicate them as intergenerational neural mediators. By closely examining how individual …
implicate them as intergenerational neural mediators. By closely examining how individual …
[HTML][HTML] Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development
Leucine-rich repeat (LRR) proteins have recently been identified as important regulators of
synapse development and function, but for many LRR proteins the ligand-receptor …
synapse development and function, but for many LRR proteins the ligand-receptor …
Heparan sulfate proteoglycans as emerging players in synaptic specificity
G Condomitti, J De Wit - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Neural circuits consist of distinct neuronal cell types connected in specific patterns. The
specificity of these connections is achieved in a series of sequential developmental steps …
specificity of these connections is achieved in a series of sequential developmental steps …
Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion
The personality traits of neuroticism and extraversion are predictive of a number of social
and behavioural outcomes and psychiatric disorders. Twin and family studies have reported …
and behavioural outcomes and psychiatric disorders. Twin and family studies have reported …