Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Hyperpolarized NMR Spectroscopy: d‐DNP, PHIP, and SABRE Techniques

KV Kovtunov, EV Pokochueva… - Chemistry–An Asian …, 2018 - Wiley Online Library
The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …

Hyperpolarising pyruvate through signal amplification by reversible exchange (SABRE)

W Iali, SS Roy, BJ Tickner, F Ahwal… - Angewandte …, 2019 - Wiley Online Library
Hyperpolarisation methods that premagnetise agents such as pyruvate are currently
receiving significant attention because they produce sensitivity gains that allow disease …

Low-field and benchtop NMR

B Blümich - Journal of Magnetic Resonance, 2019 - Elsevier
NMR started at low field. Important discoveries like the first observation of NMR in
condensed matter, the spin echo, NMR for chemical analysis, Fourier NMR spectroscopy …

SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization

DA Barskiy, S Knecht, AV Yurkovskaya… - Progress in Nuclear …, 2019 - Elsevier
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1–13C] pyruvate in vivo

K MacCulloch, A Browning, DOG Bedoya… - Journal of magnetic …, 2023 - Elsevier
Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as
Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to …

Signal amplification by reversible exchange (SABRE): From discovery to diagnosis

PJ Rayner, SB Duckett - Angewandte Chemie International …, 2018 - Wiley Online Library
Signal amplification by reversible exchange (SABRE) turns typically weak magnetic
resonance responses into strong signals making previously impractical measurements …

A leap forward in iridium–NHC catalysis: new horizons and mechanistic insights

M Iglesias, LA Oro - Chemical Society Reviews, 2018 - pubs.rsc.org
This review summarises the most recent advances in Ir–NHC catalysis while revisiting all the
classical reactions in which this type of catalyst has proved to be active. The influence of the …

Fine-tuning the efficiency of para-hydrogen-induced hyperpolarization by rational N-heterocyclic carbene design

PJ Rayner, P Norcott, KM Appleby, W Iali… - Nature …, 2018 - nature.com
Iridium N-heterocyclic carbene (NHC) complexes catalyse the para-hydrogen-induced
hyperpolarization process, Signal Amplification by Reversible Exchange (SABRE). This …