Macrophages reside in virtually every organ. First arising during embryogenesis,
macrophages replenish themselves in the adult through a combination of self-renewal and …

As a principal aspect of their scavenging function, splenic and hepatic macrophages
phagocytize and degrade senescent and damaged erythrocytes to recover iron, mainly for …

Retromer is a membrane-associated heteropentameric coat complex that functions in the
endosome-to-Golgi retrieval of the cation-independent mannose-6-phosphate receptor, the …

Plants require trace levels of manganese (Mn) for survival, as it is an essential cofactor in
oxygen metabolism, especially O2 production via photosynthesis and the disposal of …

The Natural resistance-associated macrophage protein (Nramp) family of transition metal
transporters enables uptake and trafficking of essential micronutrients that all organisms …

During the course of infection, many natural defenses are set up along the boundaries of the
host-pathogen interface. Key among these is the host response to withhold metals to restrict …

This review is focused on the mammalian SLC11 and SLC40 families and their roles in iron
homeostasis. The SLC11 family is composed of two members, SLC11A1 and SLC11A2 …

Macrophages exert multiple important roles in iron metabolism. As scavengers, splenic and
hepatic macrophages phagocytize and degrade senescent and damaged erythrocytes to …

Covering: up to the end of 2009 Detecting deficiency and excess of different metal ions is
fundamental for every organism. Our understanding of how metals are detected by bacteria …

Ninety per cent of the 500 000 annual new cases of visceral leishmaniasis (VL) occur in
India/Bangladesh/Nepal, Sudan and Brazil. Importantly, 80–90% of human infections are …