The human nervous system is one of the most complicated systems in nature. Complex
nonlinear behaviours have been shown from the single neuron level to the system level. For …

Sensory processing and sensorimotor integration are abnormal in dystonia, including
impaired modulation of beta-corticomuscular coherence. However, cortex–muscle …

The cortical motor system can be reorganized following a stroke, with increased recruitment
of the contralesional hemisphere. However, it is unknown whether a similar hemispheric …

Following a hemiparetic stroke, individuals exhibit altered motor unit firing patterns during
voluntary muscle contractions, including impairments in firing rate modulation and …

A hallmark impairment in a hemiparetic stroke is a loss of independent joint control resulting
in abnormal co-activation of shoulder abductor and elbow flexor muscles in their paretic arm …

Previous studies found that post-stroke motor impairments are associated with damage to
the lesioned corticospinal tract and a maladaptive increase in indirect contralesional motor …

Following a stroke, compensation for the loss of ipsilesional corticospinal and corticobulbar
projections, results in increased reliance on contralesional motor pathways during paretic …

Stretch reflexes are crucial for performing accurate movements and providing rapid
corrections for unpredictable perturbations. Stretch reflexes are modulated by supraspinal …

After stroke, paretic arm muscles are constantly exposed to abnormal neural drive from the
injured brain. As such, hypertonia, broadly defined as an increase in muscle tone, is …

Voluntary movement is generated through the coordinated action of excitatory, inhibitory,
and neuromodulatory commands to spinal motoneurons. A primary component of these …