Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM)
remodeling endopeptidases that have the capacity to degrade almost every component of …

Matrix metalloproteinases (MMPs) have long been associated with cancer-cell invasion and
metastasis. This provided the rationale for clinical trials of MMP inhibitors, unfortunately with …

Atherosclerosis underlies most cardiovascular diseases, and is accepted as a primary cause
of mortality worldwide. Proteases have been implicated in the development and progression …

Matrix metalloproteinases (MMPs) are a family of enzymes that proteolytically degrade
various components of the extracellular matrix (ECM). Angiogenesis is the process of …

The biological roles of the matrix metalloproteinases (MMPs) have been traditionally
associated with the degradation and turnover of most of the components of the extracellular …

Matrix metalloproteinases (MMPs) are the major protease family responsible for the
cleavage of the matrisome (global composition of the extracellular matrix (ECM) proteome) …

The matrix metalloproteinases (MMP)-2 and-9, also known as the gelatinases have been
long recognized as major contributors to the proteolytic degradation of extracellular matrix …

Sprouting angiogenesis is an invasive process that involves proteolytic activities required for
the degradation of the endothelial basement membrane, cell migration with removal of …

Matrix metalloproteinases (MMPs) are a family of zinc dependent extracellular matrix (ECM)
remodelling endopeptidases having the ability to degrade almost all components of …

Matrix metalloproteinases (MMPs) constitute a family of more than 20 endopeptidases.
Identification of specific matrix and non-matrix components as MMP substrates showed that …