Dearomatization reactions provide a synthetic connection between readily available, simple
aromatic starting materials and more saturated intermediates of greater molecular …

Conspectus The implementation of any chemical reaction in a structurally complex setting
(King, SMJ Org. Chem. 2014, 79, 8937) confronts structurally defined barriers: steric …

Dearomative photocycloaddition of monocyclic arenes is an appealing strategy for
comprehending the concept of “escape from flatland”. This brings the replacement of readily …

Arene hydrogenation provides direct access to saturated carbo‐and heterocycles and thus
its strategic application may be used to shorten synthetic routes. This powerful …

Linkage chemistry and functional molecules derived from the stereogenic sulfur (VI) centre
have important applications in organic synthesis, bioconjugation, drug discovery …

We report that the dearomative [4+ 2] cycloaddition between 1, 2-dihydro-1, 2, 4, 5-tetrazine-
3, 6-diones (TETRADs) and benzenes, naphthalenes, or N-heteroaromatic compounds …

The dearomatization of aromatic compounds is an important synthetic strategy used in
accessing complex three‐dimensional structures from simple aromatic precursors. This …

Herein, a general strategy for chemo‐and regioselective 1, 2‐reduction of chromium‐bound
arenes was developed, thus providing rapid access to 1, 3‐cyclohexadienes. Selective …

Heterocycles are the backbone of modern medical chemistry and drug development. The
derivatization of “an olefin” inside aromatic rings represents an ideal approach to access …

Direct epoxidation of aromatic nuclei by cytochrome P450 monooxygenases is one of the
major metabolic pathways of arenes in eukaryotes. The resulting arene oxides serve as …