Injuries to the spinal cord result in permanent disabilities that limit daily life activities. The
main reasons for these poor outcomes are the limited regenerative capacity of central …

Spinal cord injury (SCI) affects an estimated three million persons worldwide, with∼
180,000 new cases reported each year leading to severe motor and sensory functional …

Axons differ in their growth potential: whereas during development, axons rapidly grow to
their targets, in the adult mammalian, CNS axons have lost their ability to grow and therefore …

Axons in the adult mammalian central nervous system fail to regenerate after spinal cord
injury. Neurons lose their capacity to regenerate during development, but the intracellular …

Traumatic spinal cord injury (SCI) is the devastating neurological damage to the spinal cord
that becomes more complicated in the secondary phase. The secondary injury comes with …

Spinal cord injury (SCI) is a disastrous event causing irreversible loss of both sensory and
motor function. After SCI, both ascending dorsal column axons and descending corticospinal …

High-level spinal cord injury (SCI) can disrupt cardiovascular autonomic function. However,
the evolution of cardiovascular autonomic function in the acute phase following injury is …

Despite promising basic science discoveries and a surge in clinical trials, the quest for
effective treatments that restore neurological function after spinal cord injury lags on. While" …

Background Complications arising from acute traumatic spinal cord injury (SCI) are routinely
managed by various pharmacological interventions. Despite decades of clinical application …

BACKGROUND CONTEXT Traumatic spinal cord injury (SCI) leads to severe motor and
sensory functional impairments that affect personal and social behaviors. Medical …