Genetics of atrial fibrillation: an update
HM Campbell, XHT Wehrens - Current opinion in cardiology, 2018 - journals.lww.com
Genetics of atrial fibrillation: an update : Current Opinion in Cardiology Genetics of atrial
fibrillation: an update : Current Opinion in Cardiology Log in or Register Subscribe to journalSubscribe …
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Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model
MM Collins, G Ahlberg, CV Hansen… - Proceedings of the …, 2019 - National Acad Sciences
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The major AF
susceptibility locus 4q25 establishes long-range interactions with the promoter of PITX2, a …
susceptibility locus 4q25 establishes long-range interactions with the promoter of PITX2, a …
[HTML][HTML] The Generation of Genetically Engineered Human Induced Pluripotent Stem Cells Overexpressing IFN-β for Future Experimental and Clinically Oriented …
O Sheveleva, E Protasova, E Grigor'eva… - International Journal of …, 2024 - mdpi.com
Induced pluripotent stem cells (iPSCs) can be generated from various adult cells, genetically
modified and differentiated into diverse cell populations. Type I interferons (IFN-Is) have …
modified and differentiated into diverse cell populations. Type I interferons (IFN-Is) have …
Genetics of Atrial Fibrilation: In search of novel therapeutic targets
E Lozano-Velasco, C Garcia-Padilla… - … Current Drug Targets …, 2019 - ingentaconnect.com
Atrial fibrillation (AF) is the most frequent arrhythmogenic disease in humans, ranging from
2% in the general population and rising up to 10-12% in 80+ years. Genetic analyses of AF …
2% in the general population and rising up to 10-12% in 80+ years. Genetic analyses of AF …
PITX2 gain-of-function mutation associated with atrial fibrillation alters mitochondrial activity in human iPSC atrial-like cardiomyocytes
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide; however, the
underlying causes of AF initiation are still poorly understood, particularly because currently …
underlying causes of AF initiation are still poorly understood, particularly because currently …
Novel PITX2 homeodomain-contained mutations from ATRIAL fibrillation patients deteriorate calcium homeostasis
A Herraiz-Martínez, C Tarifa, E Lozano-Velasco… - Hearts, 2021 - mdpi.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the human population, with
an estimated incidence of 1–2% in young adults but increasing to more than 10% in 80+ …
an estimated incidence of 1–2% in young adults but increasing to more than 10% in 80+ …
心房颤动相关基因及其心电图改变
谷娅楠， 卢慧， 李冰 - 大连医科大学学报, 2019 - journal.dmu.edu.cn
近年来分子生物学的发展不仅为深入阐明房颤的分子机制提供了理论基础,
而且为实现房颤的基因诊断和针对性, 特异性治疗带来了新的思路. 房颤相关变异基因不但与房 …
而且为实现房颤的基因诊断和针对性, 特异性治疗带来了新的思路. 房颤相关变异基因不但与房 …
[HTML][HTML] Generation of the induced pluripotent stem cell line UNIBSi017-A from an individual with cardiospondylocarpofacial syndrome and the MAP3K7 c. 737-7A> G …
S Calamaio, M Serzanti, S Morlino, M Massardi… - Stem Cell Research, 2022 - Elsevier
TAK1 is a serine threonine kinase that mediates signal transduction induced by TGFβ and
bone morphogenetic proteins, and controls a variety of cell functions by modulating the …
bone morphogenetic proteins, and controls a variety of cell functions by modulating the …
Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in …
RH Oakley, MJ Campen, ML Paffett, X Chen… - BMC Medical …, 2018 - Springer
Background We recently identified a role for the muscle-specific ubiquitin ligase MuRF1 in
right-sided heart failure secondary to pulmonary hypertension induced by chronic hypoxia …
right-sided heart failure secondary to pulmonary hypertension induced by chronic hypoxia …