Drug screening is a long and costly process confronted with low productivity and challenges
in using animals, which limit the discovery of new drugs. To improve drug screening efficacy …

Living sample viability measurement is an extremely common process in medical,
pharmaceutical, and biological fields, especially drug pharmacology and toxicology …

Screening of biochemical interactions becomes simpler, less expensive, and more accurate
when labels, such as fluorescent dyes, radioactive markers, and colorimetric reactions, are …

Withania sominifera (Indian ginseng) was transformed by Agrobacterium rhizogenes.
Explants from seedling roots, stems, hypocotyls, cotyledonary nodal segments, cotyledons …

Mitochondrial dysfunction has been associated with a variety of currently marketed
therapeutics and has also been implicated in many disease states. Alterations in the rate of …

High throughput screening (HTS) of molecular analytes is in high demand from and
implemented in many areas of chemistry, medicine and industrial biotechnology including …

Cytotoxicity testing allows determining whether a compound or extract contains significant
quantities of biologically harmful chemicals. Cytotoxicity test methods are useful for …

Mitochondrial dysfunction is a common mechanism of drug-induced toxicity. Early
identification of new chemical entities (NCEs) that perturb mitochondrial function is of …

The c-myc proto-oncogene is rapidly activated by serum and regulates genes involved in
metabolism and cell cycle progression. This gene is thereby uniquely poised to coordinate …

Despite theoretical obstacles associated with performing cell-based assays in high-density
formats (microplates with at least 384 wells), it is becoming clear that the pharmaceutical …