The role of quantitative hepatitis B surface antigen revisited

M Cornberg, VWS Wong, S Locarnini, M Brunetto… - Journal of …, 2017 - Elsevier
In the past 10 years, there has been a lot of enthusiasm surrounding the use of serum
hepatitis B surface antigen (HBsAg) quantification to predict disease activity and monitor …

Hepatitis B virus: advances in prevention, diagnosis, and therapy

MH Nguyen, G Wong, E Gane, JH Kao… - Clinical microbiology …, 2020 - Am Soc Microbiol
Currently, despite the use of a preventive vaccine for several decades as well as the use of
effective and well-tolerated viral suppressive medications since 1998, approximately 250 …

Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update

SK Sarin, M Kumar, GK Lau, Z Abbas, HLY Chan… - Hepatology …, 2016 - Springer
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest
rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection …

Serum hepatitis B core-related antigen (HBcrAg) correlates with covalently closed circular DNA transcriptional activity in chronic hepatitis B patients

B Testoni, F Lebossé, C Scholtes, F Berby… - Journal of …, 2019 - Elsevier
Background & Aims It has been proposed that serum hepatitis B core-related antigen
(HBcrAg) reflects intrahepatic covalently closed circular (ccc) DNA levels. However, the …

Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update

YF Liaw, JH Kao, T Piratvisuth, HLY Chan… - Hepatology …, 2012 - Springer
Large volume of new data on the natural history and treatment of chronic hepatitis B virus
(HBV) infection have become available since 2008. These include further studies in …

High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load

TC Tseng, CJ Liu, HC Yang, TH Su, CC Wang… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Patients with chronic hepatitis B virus (HBV) infection have a high
risk for developing hepatocellular carcinoma (HCC). Patients with lower levels of hepatitis B …

[HTML][HTML] KASL clinical practice guidelines for management of chronic hepatitis B

Korean Association for the Study of the … - Clinical and …, 2019 - ncbi.nlm.nih.gov
Diseases (AASLD) also presented and continued to revise their clinical practice guidelines,
and the latest updates were in 2015, 2017, and 2018. However, since the medical …

Effects of hepatitis B surface antigen on virus-specific and global T cells in patients with chronic hepatitis B virus infection

N Le Bert, US Gill, M Hong, K Kunasegaran, DZM Tan… - Gastroenterology, 2020 - Elsevier
Background & Aims Chronic hepatitis B virus (HBV) infection is characterized by the
presence of defective viral envelope proteins (hepatitis B surface antigen [HBsAg]) and the …

Prediction models of long‐term cirrhosis and hepatocellular carcinoma risk in chronic hepatitis B patients: risk scores integrating host and virus profiles

MH Lee, HI Yang, J Liu, R Batrla‐Utermann… - …, 2013 - Wiley Online Library
Integrating host and HBV characteristics, this study aimed to develop models for predicting
long‐term cirrhosis and hepatocellular carcinoma (HCC) risk in chronic hepatitis B virus …

[HTML][HTML] Hepatitis B surface antigen quantification: why and how to use it in 2011–a core group report

HLY Chan, A Thompson, M Martinot-Peignoux… - Journal of …, 2011 - Elsevier
Quantitative HBsAg had been suggested to be helpful in management of HBV, but assays
were cumbersome. The recent availability of commercial quantitative assays has restarted …