Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …

Elucidation of the process of sex chromosome differentiation is necessary to understand the
dynamics of evolutionary mechanisms in organisms. The W sex chromosome of the …

Proteogenomics, the alliance of proteomics, transcriptomics, genomics and bioinformatics,
was first proposed for refining genome annotation using experimental data acquired on …

Introduction Exposure to space conditions during crewed long-term exploration missions
can cause several health risks for astronauts. Space radiation, isolation and microgravity are …

Background: Glioblastoma is a common malignant neuroepithelial neoplasm with poor
clinical outcomes and limited treatment options. It is extremely important to search and …

Differential co-expression network analyses have recently become an important step in the
investigation of cellular differentiation and dysfunctional gene-regulation in cell and tissue …

Glioblastoma multiforme (GBM) is the most common infiltrating lethal tumor of the brain.
Tumor heterogeneity and the precise characterization of GBM remain challenging, and the …

Finding protein evidence (PE) for protein coding genes is a primary task of the Phase I
Chromosome-Centric Human Proteome Project (C-HPP). Currently, there are 2948 PE level …

The importance of olfaction to human health and disease is often underappreciated.
Olfactory dysfunction has been reported in association with a host of common complex …

The acrosome is single, large, dense-core secretory granule overlying the nucleus of most
mammalian spermatozoa. Its exocytosis, the acrosome reaction, is a crucial event during …