Many parasitic worms possess complex and intriguing life cycles, and schistosomes are no
exception. To exit the human body and progress to their successive snail host, Schistosoma …

Pyrimidines are essential for the cell survival and proliferation of living parasitic organisms,
such as Helicobacter pylori, Plasmodium falciparum and Schistosoma mansoni, that are …

In the next century, global warming, due to changes in climatic factors, is expected to have
an enormous influence on the interactions between pathogens and their hosts. Over the …

Background. Schistosomiasis is caused by Schistosoma mansoni and S. haematobium in
Africa. These schistosome parasites use freshwater snail intermediate hosts to complete …

Background. Schistosomiasis is one of the neglected tropical diseases causing a serious
human health problem in Ethiopia. Praziquantel is the only drug that has been used for the …

Conventional microscopy is the standard procedure for the diagnosis of schistosomiasis,
despite its limited sensitivity, reliance on skilled personnel, and the fact that it is error prone …

Despite being one of the most commonly used drugs, the molecular mechanism of action of
the anthelmintic praziquantel remains unknown. There are some unusual features of this …

Praziquantel (PZQ) is the only drug available for community-based control programs which
aim to reduce the prevalence and morbidity associated with schistosomiasis. Here, we …

Schistosomiasis is a parasitic neglected disease with praziquantel (PZQ) utilized as the
main drug for treatment, despite its low effectiveness against early stages of the worm. To …

Schistosomiasis is a parasitic flatworm disease that infects over 200 million people
worldwide, especially in poor communities. Treatment and control of the disease rely on just …