Comprehensive invasive and noninvasive approach to the right ventricle–pulmonary circulation unit: state of the art and clinical and research implications
HC Champion, ED Michelakis, PM Hassoun - Circulation, 2009 - Am Heart Assoc
markers such as right atrial pressure, cardiac output, and mean PAP. 8 Importantly, this
procedure has been shown to be safe, with no deaths reported in the National Institutes of …
procedure has been shown to be safe, with no deaths reported in the National Institutes of …
Early detection of pulmonary arterial hypertension
EMT Lau, M Humbert, DS Celermajer - Nature Reviews Cardiology, 2015 - nature.com
Pulmonary arterial hypertension (PAH) remains an incurable disease associated with an
unacceptably high early mortality, despite advances in therapeutic options. The disease is …
unacceptably high early mortality, despite advances in therapeutic options. The disease is …
Expanding applications of pulmonary MRI in the clinical evaluation of lung disorders: Fleischner Society position paper
H Hatabu, Y Ohno, WB Gefter, G Parraga, B Madore… - Radiology, 2020 - pubs.rsna.org
Pulmonary MRI provides structural and quantitative functional images of the lungs without
ionizing radiation, but it has had limited clinical use due to low signal intensity from the lung …
ionizing radiation, but it has had limited clinical use due to low signal intensity from the lung …
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients
ED Michelakis, V Gurtu, L Webster, G Barnes… - Science translational …, 2017 - science.org
Pulmonary arterial hypertension (PAH) is a progressive vascular disease with a high
mortality rate. It is characterized by an occlusive vascular remodeling due to a pro …
mortality rate. It is characterized by an occlusive vascular remodeling due to a pro …
Optimized 3D ultrashort echo time pulmonary MRI
Purpose To optimize 3D radial ultrashort echo time MRI for high resolution whole‐lung
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …
Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)
Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …
remains a life-shortening condition. There have been significant advances in imaging …
Noninvasive estimation of PA pressure, flow, and resistance with CMR imaging: derivation and prospective validation study from the ASPIRE registry
Objectives: The aim of this study was to develop a composite numerical model based on
parameters from cardiac magnetic resonance (CMR) imaging for noninvasive estimation of …
parameters from cardiac magnetic resonance (CMR) imaging for noninvasive estimation of …
Dual-energy CT angiography for assessment of regional pulmonary perfusion in patients with chronic thromboembolic pulmonary hypertension: initial experience
ETD Hoey, S Mirsadraee… - American Journal of …, 2011 - Am Roentgen Ray Soc
OBJECTIVE. This study assessed the utility of dual-energy pulmonary CT angiography
(CTA) for noninvasive assessment of regional pulmonary perfusion in patients with chronic …
(CTA) for noninvasive assessment of regional pulmonary perfusion in patients with chronic …
Early detection of pulmonary vascular disease in pulmonary arterial hypertension: time to move forward
EMT Lau, A Manes, DS Celermajer… - European heart …, 2011 - academic.oup.com
Pulmonary arterial hypertension (PAH) can be a rapidly progressive disorder and is
associated with high rate of mortality, despite medical intervention. With the availability of …
associated with high rate of mortality, despite medical intervention. With the availability of …
MR and CT imaging for the evaluation of pulmonary hypertension
Imaging plays a central role in the diagnosis and management of all forms of pulmonary
hypertension (PH). Although Doppler echocardiography is essential for the evaluation of PH …
hypertension (PH). Although Doppler echocardiography is essential for the evaluation of PH …