Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

The histaminergic system in the brain is a phylogenetically old group of neurons that project
to most of the central nervous system. It holds a key position in the regulation of basic body …

Since the cloning of the histamine H3 receptor cDNA in 1999 by Lovenberg and co-workers,
this histamine receptor has gained the interest of many pharmaceutical companies as a …

The histamine H3 receptor, first described in 1983 as a histamine autoreceptor and later
shown to also function as a heteroreceptor that regulates the release of other …

H3 antagonists increase the release of brain histamine, acetylcholine, noradrenaline, and
dopamine, neurotransmitters that are known to modulate cognitive processes. The ability to …

Histamine H3 receptor inverse agonists are known to enhance the activity of histaminergic
neurons in brain and thereby promote vigilance and cognition. 1-{3-[3-(4-Chlorophenyl) …

Neuropharmacology of the histaminergic neuron system in the brain and its relationship with
behavioral disorders - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …

The histamine H 3 receptor was discovered 15 years ago, and many potent and selective H
3 receptor agonists and antagonists have since been developed. Currently, much attention …

Using an in vivo microdialysis technique coupled with HPLC-fluorometry, the release of
neuronal histamine from the anterior hypothalamic area was monitored continuously in …

Histaminergic neurons in the tuberomammillary nucleus (TMN) are an important component
of the ascending arousal system and may form part of a “flip–flop switch” hypothesized to …