Unraveling the roles of plant specialized metabolites: using synthetic biology to design molecular biosensors
C Garagounis, N Delkis, KK Papadopoulou - New Phytologist, 2021 - Wiley Online Library
Plants are a rich source of specialized metabolites with a broad range of bioactivities and
many applications in human daily life. Over the past decades significant progress has been …
many applications in human daily life. Over the past decades significant progress has been …
Simulation intelligence: Towards a new generation of scientific methods
The original" Seven Motifs" set forth a roadmap of essential methods for the field of scientific
computing, where a motif is an algorithmic method that captures a pattern of computation …
computing, where a motif is an algorithmic method that captures a pattern of computation …
Standardization in synthetic biology: an engineering discipline coming of age
T Decoene, B De Paepe, J Maertens… - Critical reviews in …, 2018 - Taylor & Francis
Background: Leaping DNA read-and-write technologies, and extensive automation and
miniaturization are radically transforming the field of biological experimentation by providing …
miniaturization are radically transforming the field of biological experimentation by providing …
SynBioHub: a standards-enabled design repository for synthetic biology
The SynBioHub repository (https://synbiohub. org) is an open-source software project that
facilitates the sharing of information about engineered biological systems. SynBioHub …
facilitates the sharing of information about engineered biological systems. SynBioHub …
iBioSim 3: A Tool for Model-Based Genetic Circuit Design
The iBioSim tool has been developed to facilitate the design of genetic circuits via a model-
based design strategy. This paper illustrates the new features incorporated into the tool for …
based design strategy. This paper illustrates the new features incorporated into the tool for …
Genetic circuit dynamics: hazard and glitch analysis
P Fontanarrosa, H Doosthosseini… - ACS synthetic …, 2020 - ACS Publications
Multiple input changes can cause unwanted switching variations, or glitches, in the output of
genetic combinational circuits. These glitches can have drastic effects if the output of the …
genetic combinational circuits. These glitches can have drastic effects if the output of the …
A network approach to genetic circuit designs
M Crowther, A Wipat, Á Goñi-Moreno - ACS synthetic biology, 2022 - ACS Publications
As genetic circuits become more sophisticated, the size and complexity of data about their
designs increase. The data captured goes beyond genetic sequences alone; information …
designs increase. The data captured goes beyond genetic sequences alone; information …
Synthetic biology knowledge system
The Synthetic Biology Knowledge System (SBKS) is an instance of the SynBioHub
repository that includes text and data information that has been mined from papers …
repository that includes text and data information that has been mined from papers …
A standard-enabled workflow for synthetic biology
A synthetic biology workflow is composed of data repositories that provide information about
genetic parts, sequence-level design tools to compose these parts into circuits, visualization …
genetic parts, sequence-level design tools to compose these parts into circuits, visualization …
A computational workflow for the automated generation of models of genetic designs
Computational models are essential to engineer predictable biological systems and to scale
up this process for complex systems. Computational modeling often requires expert …
up this process for complex systems. Computational modeling often requires expert …