This working group of the International Society of Hepatic Encephalopathy and Nitrogen
Metabolism (ISHEN) was commissioned to summarize and update current efforts in the …

Hemolysis represents an important source of error associated with the pre-analytical phase.
Improving the protocols for detection, measurement, management of the parameters affected …

Hyperammonaemia (HA) as a consequence of numerous primary or secondary causes,
gives rise to clinical manifestations due to its toxic effects on the brain. The neurological …

Various methods are currently used interchangeably in the preparation of hemolyzed
samples for hemolysis interference studies [1]. For correct interpretation of the results in …

Background Severe hyperammonaemia is associated with significant morbidity and
mortality. Rapid analysis and reporting of ammonia results is essential to prevent patient …

Background Some clinical chemistry measurement methods are vulnerable to interference if
hemolyzed serum samples are used. The aims of this study were:(1) to obtain updated …

I read with great interest the recent article by Rychert et al, 1 who evaluated the frequency of
laboratory-developed tests (LDTs) in an academic medical center. The authors determined …

目的探讨内源性干扰物质血红蛋白(Hb), 胆红素(Bil) 和乳糜微粒对酶速率法[谷氨酸脱氢酶(
GLDH) 法] 和干化学法检测血氨的影响. 方法根据美国临床实验室标准化协会(CLSI) EP7-A2 …

• There is limited knowledge if the method used for preparation of hemolyzed samples for
interference studies can affect the test results.• Studies have shown that interference caused …

Background Preanalytic factors such as time and temperature can have significant effects on
laboratory test results. For example, ammonium concentration will increase 31% in blood …