While mechanobiological processes employ diverse mechanisms, at their heart are force-
induced perturbations in the structure and dynamics of molecules capable of triggering …

Bacteria represent one of the most evolutionarily successful groups of organisms to inhabit
Earth. Their world is awash with mechanical cues, probably the most ancient form of which …

GsMTx4 is a spider venom peptide that inhibits cationic mechanosensitive channels (MSCs).
It has six lysine residues that have been proposed to affect membrane binding. We …

Mechanosensitive (MS) channels of small (MscS) and large (MscL) conductance are the
major players in the protection of bacterial cells against hypoosmotic shock. Although a …

Single-celled organisms must survive exposure to environmental extremes. Perhaps one of
the most variable and potentially life-threatening changes that can occur is that of a rapid …

The ability to respond to unanticipated increases in volume is a fundamental property of
cells, essential for cellular integrity in the face of osmotic challenges. Plants must manage …

Piezo ion channels are sensors of mechanical forces and mediate a wide range of
physiological mechanotransduction processes. More than a decade of intense research has …

Cells perceive force through a variety of molecular sensors, of which the mechanosensitive
ion channels are the most efficient and act the fastest. These channels apparently evolved to …

Like many other organisms, plants are capable of sensing and responding to mechanical
stimuli such as touch, osmotic pressure, and gravity. One mechanism for the perception of …

Plants, like other organisms, are facing multiple mechanical constraints generated both in
their tissues and by the surrounding environments. They need to sense and adapt to these …