[HTML][HTML] Efficacy and safety of ruxolitinib cream for the treatment of atopic dermatitis: results from 2 phase 3, randomized, double-blind studies
K Papp, JC Szepietowski, L Kircik, D Toth… - Journal of the American …, 2021 - Elsevier
Background Ruxolitinib (RUX) cream demonstrated potent anti-inflammatory and antipruritic
efficacy in a phase 2 study in adults with atopic dermatitis (AD). Objective To evaluate 8 …
efficacy in a phase 2 study in adults with atopic dermatitis (AD). Objective To evaluate 8 …
Approach to the assessment and management of adult patients with atopic dermatitis: a consensus document. Section II: tools for assessing the severity of atopic …
MJ Gooderham, R Bissonnette… - Journal of …, 2018 - journals.sagepub.com
Clinicians rely on clinical measures to define the severity of atopic dermatitis and assess
outcomes of therapy. These measures can be objective (ie, physician assessments of …
outcomes of therapy. These measures can be objective (ie, physician assessments of …
Dupilumab provides favorable safety and sustained efficacy for up to 3 years in an open-label study of adults with moderate-to-severe atopic dermatitis
Background Management of moderate-to-severe atopic dermatitis (AD) commonly requires
long-term treatment. Objective The aim of this study was to report the safety and efficacy of …
long-term treatment. Objective The aim of this study was to report the safety and efficacy of …
Patient-reported outcomes and quality of life measures in atopic dermatitis
PP Vakharia, D Cella, JI Silverberg - Clinics in Dermatology, 2018 - Elsevier
Atopic dermatitis (AD) is a complex and heterogeneous disorder with a profound symptom
burden and harmful impact on multiple domains of quality of life (QOL). Many different …
burden and harmful impact on multiple domains of quality of life (QOL). Many different …
Measuring atopic eczema control and itch intensity in clinical practice: a consensus statement from the Harmonising Outcome Measures for Eczema in Clinical …
YA Leshem, JR Chalmers, C Apfelbacher… - JAMA …, 2022 - jamanetwork.com
Importance Measuring outcomes in clinical practice can aid patient care, quality
improvement, and real-world evidence generation. The Harmonising Outcome Measures for …
improvement, and real-world evidence generation. The Harmonising Outcome Measures for …
What are the best endpoints for Eczema Area and Severity Index and Scoring Atopic Dermatitis in clinical practice? A prospective observational study
Background Multiple strategies have been used to evaluate the minimal important change
(MIC) of the Eczema Area and Severity Index (EASI) and Scoring Atopic Dermatitis …
(MIC) of the Eczema Area and Severity Index (EASI) and Scoring Atopic Dermatitis …
Baseline body surface area and itch severity define response to baricitinib in patients with moderate-to-severe atopic dermatitis at week 16
JP Thyssen, M de Bruin-Weller, A Costanzo… - Advances in …, 2023 - Springer
Introduction Atopic dermatitis (AD) is a chronic, inflammatory skin disease characterized by
heterogeneous clinical phenotypes and high symptom burden, especially through itch …
heterogeneous clinical phenotypes and high symptom burden, especially through itch …
An anti-OX40 antibody to treat moderate-to-severe atopic dermatitis: a multicentre, double-blind, placebo-controlled phase 2b study
Background OX40 is crucial for T-cell differentiation and memory induction. The anti-OX40
antibody, rocatinlimab inhibits the OX40 pathway. We evaluated the efficacy and safety of …
antibody, rocatinlimab inhibits the OX40 pathway. We evaluated the efficacy and safety of …
Treatment options for DOCK8 deficiency‐related severe dermatitis
A Ollech, J Mashiah, A Lev, AJ Simon… - The Journal of …, 2021 - Wiley Online Library
Background Cutaneous manifestations of dedicator of cytokinesis 8 gene (DOCK8)
deficiency, a combined type of T and B cell immunodeficiency, previously designated as …
deficiency, a combined type of T and B cell immunodeficiency, previously designated as …
The role of the nurse in the care and management of patients with atopic dermatitis
H van Os-Medendorp, E Deprez, N Maes, S Ryan… - Bmc Nursing, 2020 - Springer
Background The purpose of this paper is to provide an overview of key aspects of
specialised dermatology nursing practice in the management of patients with moderate to …
specialised dermatology nursing practice in the management of patients with moderate to …