[HTML][HTML] Guanosine: a neuromodulator with therapeutic potential in brain disorders
D Lanznaster, T Dal-Cim, TCB Piermartiri… - Aging and …, 2016 - ncbi.nlm.nih.gov
Guanosine is a purine nucleoside with important functions in cell metabolism and a
protective role in response to degenerative diseases or injury. The past decade has seen …
protective role in response to degenerative diseases or injury. The past decade has seen …
Proposal of a guanine-based purinergic system in the mammalian central nervous system
Guanine-based purines have been traditionally studied as modulators of intracellular
processes, mainly G-protein activity. However, they also exert several extracellular effects …
processes, mainly G-protein activity. However, they also exert several extracellular effects …
Voltammetric determination of adenosine and guanosine using fullerene-C60-modified glassy carbon electrode
A fullerene-C60-modified glassy carbon electrode (GCE) is used for the simultaneous
determination of adenosine and guanosine by differential pulse voltammetry. Compared to a …
determination of adenosine and guanosine by differential pulse voltammetry. Compared to a …
Oligodendrocyte-protection and remyelination post-spinal cord injuries: a review
M Mekhail, G Almazan, M Tabrizian - Progress in neurobiology, 2012 - Elsevier
In the past four decades, the main focus of investigators in the field of spinal cord
regeneration has been to devise therapeutic measures that enhance neural regeneration …
regeneration has been to devise therapeutic measures that enhance neural regeneration …
Guanosine and its role in neuropathologies
Guanosine is a purine nucleoside thought to have neuroprotective properties. It is released
in the brain under physiological conditions and even more during pathological events …
in the brain under physiological conditions and even more during pathological events …
Electrocatalytic oxidation behavior of guanosine at graphene, chitosan and Fe3O4 nanoparticles modified glassy carbon electrode and its determination
H Yin, Y Zhou, Q Ma, S Ai, Q Chen, L Zhu - Talanta, 2010 - Elsevier
A graphene, chitosan and Fe3O4 nanoparticles (nano-Fe3O4) modified glassy carbon
electrode (graphene–chitosan/nano-Fe3O4/GCE) was fabricated. The modified electrode …
electrode (graphene–chitosan/nano-Fe3O4/GCE) was fabricated. The modified electrode …
Swimming training prevents pentylenetetrazol‐induced inhibition of Na+, K+‐ATPase activity, seizures, and oxidative stress
Purpose: In the present study we decided to investigate whether physical exercise protects
against the electrographic, oxidative, and neurochemical alterations induced by …
against the electrographic, oxidative, and neurochemical alterations induced by …
[HTML][HTML] Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy
L Sha, X Wang, J Li, X Shi, L Wu, Y Shen… - The Journal of …, 2017 - ncbi.nlm.nih.gov
The glutamate transporter GLT-1 is critical for the maintenance of low interstitial glutamate
concentrations. Loss of GLT-1 is commonly observed in neurological disorders, including …
concentrations. Loss of GLT-1 is commonly observed in neurological disorders, including …
Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice
ER Vinadé, AP Schmidt, MES Frizzo, I Izquierdo… - Brain research, 2003 - Elsevier
Acute administration of intraperitoneal and oral guanosine has been shown to prevent
quinolinic acid and α-dendrotoxin-induced seizures in rats and mice. In this study, we …
quinolinic acid and α-dendrotoxin-induced seizures in rats and mice. In this study, we …
Subsecond detection of guanosine using fast-scan cyclic voltammetry
Guanosine is an important neuromodulator and neuroprotector in the brain and is involved
in many pathological conditions, including ischemia and neuroinflammation. Traditional …
in many pathological conditions, including ischemia and neuroinflammation. Traditional …