Redox signaling by reactive electrophiles and oxidants

S Parvez, MJC Long, JR Poganik, Y Aye - Chemical reviews, 2018 - ACS Publications
The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

Measurement of reactive oxygen species, reactive nitrogen species, and redox-dependent signaling in the cardiovascular system: a scientific statement from the …

KK Griendling, RM Touyz, JL Zweier, S Dikalov… - Circulation …, 2016 - Am Heart Assoc
Reactive oxygen species and reactive nitrogen species are biological molecules that play
important roles in cardiovascular physiology and contribute to disease initiation …

Effects of ionizing radiation on biological molecules—mechanisms of damage and emerging methods of detection

JA Reisz, N Bansal, J Qian, W Zhao… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

CE Paulsen, KS Carroll - Chemical reviews, 2013 - ACS Publications
Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS,
respectively, are produced during normal cell function and in response to various stimuli. An …

Chemistry and biology of reactive oxygen species in signaling or stress responses

BC Dickinson, CJ Chang - Nature chemical biology, 2011 - nature.com
Reactive oxygen species (ROS) are a family of molecules that are continuously generated,
transformed and consumed in all living organisms as a consequence of aerobic life. The …

Advanced photoacoustic imaging applications of near‐infrared absorbing organic nanoparticles

Y Jiang, K Pu - Small, 2017 - Wiley Online Library
Progress of nanotechnology in recent years has stimulated fast development of
nanoparticles in biomedical research. Photoacoustic (PA) imaging as an emerging non …

[HTML][HTML] Sulfenic acid chemistry, detection and cellular lifetime

V Gupta, KS Carroll - Biochimica et Biophysica Acta (BBA)-General …, 2014 - Elsevier
Background Reactive oxygen species-mediated cysteine sulfenic acid modification has
emerged as an important regulatory mechanism in cell signaling. The stability of sulfenic …

Chemical methods for mapping cysteine oxidation

LJ Alcock, MV Perkins, JM Chalker - Chemical Society Reviews, 2018 - pubs.rsc.org
Cysteine residues in proteins are subject to diverse redox chemistry. Oxidation of cysteine to
S-nitrosocysteine, cysteine sulfenic and sulfinic acids, disulfides and persulfides are a few …

Signaling functions of reactive oxygen species

HJ Forman, M Maiorino, F Ursini - Biochemistry, 2010 - ACS Publications
We review signaling by reactive oxygen species, which is emerging as a major physiological
process. However, among the reactive oxygen species, H2O2 best fulfills the requirements …

Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity

CE Paulsen, TH Truong, FJ Garcia, A Homann… - Nature chemical …, 2012 - nature.com
Protein sulfenylation is a post-translational modification of emerging importance in higher
eukaryotes. However, investigation of its diverse roles remains challenging, particularly …