Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade

Z Eslami-S, LE Cortes-Hernandez, F Thomas… - British Journal of …, 2022 - nature.com
Metastasis formation is the main cause of cancer-related death in patients with solid
tumours. At the beginning of this process, cancer cells escape from the primary tumour to the …

[HTML][HTML] Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma …

M Ilie, V Hofman, E Long, O Bordone… - Annals of …, 2014 - ncbi.nlm.nih.gov
The practice of “liquid biopsy” as a diagnostic, prognostic and theranostic tool in non-small
cell lung cancer (NSCLC) patients is an appealing approach, at least in theory, since it is …

“Sentinel” circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease

M Ilie, V Hofman, E Long-Mira, E Selva, JM Vignaud… - PloS one, 2014 - journals.plos.org
Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer. Migration of
circulating tumor cells (CTCs) into the blood stream is an early event that occurs during …

A direct comparison of CellSearch and ISET for circulating tumour-cell detection in patients with metastatic carcinomas

F Farace, C Massard, N Vimond, F Drusch… - British journal of …, 2011 - nature.com
Background: Circulating tumour cells (CTCs) can provide information on patient prognosis
and treatment efficacy. However, there is no universal method to detect CTC currently …

[HTML][HTML] A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire

N Saucedo-Zeni, S Mewes… - International …, 2012 - spandidos-publications.com
The isolation of circulating tumor cells (CTCs) from the blood of patients afflicted with solid
malignant tumors becomes increasingly important as it may serve as a 'liquid biopsy'with the …

Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications

R Harouaka, Z Kang, SY Zheng, L Cao - Pharmacology & therapeutics, 2014 - Elsevier
Circulating tumor cells (CTCs) are rare cancer cells released from tumors into the
bloodstream that are thought to have a key role in cancer metastasis. The presence of CTCs …

Detection and isolation of circulating tumor cells: principles and methods

H Esmaeilsabzali, TV Beischlag, ME Cox… - Biotechnology …, 2013 - Elsevier
Efforts to improve the clinical management of several cancers include finding better methods
for the quantitative and qualitative analysis of circulating tumor cells (CTCs). However …

Circulating tumor cells as biomarkers in prostate cancer

DC Danila, M Fleisher, HI Scher - Clinical Cancer Research, 2011 - AACR
Unmet needs in prostate cancer drug development and patient management are the ability
to monitor treatment effects and to identify therapeutic targets in a tumor at the time treatment …

Filter characteristics influencing circulating tumor cell enrichment from whole blood

FAW Coumans, G van Dalum, M Beck… - PloS one, 2013 - journals.plos.org
A variety of filters assays have been described to enrich circulating tumor cells (CTC) based
on differences in physical characteristics of blood cells and CTC. In this study we evaluate …

Circulating tumor cell enrichment based on physical properties

RA Harouaka, M Nisic… - Journal of laboratory …, 2013 - journals.sagepub.com
The metastatic dissemination and spread of malignant circulating tumor cells (CTCs)
accounts for more than 90% of cancer-related deaths. CTCs detach from a primary tumor …