Cells require tight regulation of the intracellular redox balance and consequently of reactive
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …

Drug‐induced toxicity is a key issue for public health because some side effects can be
severe and life‐threatening. These adverse effects can also be a major concern for the …

The main threats to human health from heavy metals are associated with exposure to lead,
cadmium, mercury and arsenic. Exposure to arsenic is mainly via intake of food and drinking …

Fumigation with phosphine gas is by far the most widely used treatment for the protection of
stored grain against insect pests. The development of high‐level resistance in insects now …

Mitochondria are vital cellular organelles associated with energy production as well as cell
signaling pathways. These organelles, responsible for metabolism, are highly abundant in …

Mitochondrial dysfunction in skeletal muscle has been implicated in the development of
insulin resistance, a major characteristic of type 2 diabetes. There is evidence that oxidative …

Arsenic trioxide (As2O3) is an environmental pollutant and potent toxicant to humans.
However, it also shows substantial anti-cancer activity in individuals with acute …

Mitochondrial dysfunction plays a critical role in the development of cardiac hypertrophy and
heart failure. So mitochondria are emerging as one of the important druggable targets in the …

Melatonin has been demonstrated to have anti-inflammatory and antioxidant effects. The
aim of this study was to investigate the protective effects of melatonin on arsenic trioxide (As …

Purpose Arsenic trioxide (ATO) has been shown to induce hepatic injury. Crocetin is a
primary constituent of saffron, which has been verified to have antioxidant and anti …