[HTML][HTML] Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

Z Vinarov, M Abdallah, JAG Agundez… - European Journal of …, 2021 - Elsevier
The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced drug delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

Considering sex as a biological variable in basic and clinical studies: an endocrine society scientific statement

A Bhargava, AP Arnold, DA Bangasser… - Endocrine …, 2021 - academic.oup.com
Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …

Exposure to volatile organic compounds is a risk factor for diabetes: a cross-sectional study

X Wang, W He, X Wu, X Song, X Yang, G Zhang, P Niu… - Chemosphere, 2023 - Elsevier
Currently, more studies showed that environmental chemicals were associated with the
development of diabetes. However, the effect of volatile organic compounds (VOCs) on …

Effect of gender, age and vaccine on reactogenicity and incapacity to work after COVID-19 vaccination: a survey among health care workers

I Nachtigall, M Bonsignore, S Hohenstein… - BMC Infectious …, 2022 - Springer
Background The aim of our study was to assess the impact the impact of gender and age on
reactogenicity to three COVID-19 vaccine products: Biontech/Pfizer (BNT162b2), Moderna …

Electrochemical biosensors: a nexus for precision medicine

TD Pollard, JJ Ong, A Goyanes, M Orlu, S Gaisford… - Drug Discovery …, 2021 - Elsevier
Highlights•TDM has the capacity to transform healthcare but lacks suitable portable
equipment.•ECBs can enable on-site TDM with the potential for fast, cheap, simple …

Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and …

C Perrino, P Ferdinandy, HE Bøtker… - Cardiovascular …, 2021 - academic.oup.com
Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …

Optical biosensors-Illuminating the path to personalized drug dosing

JJ Ong, TD Pollard, A Goyanes, S Gaisford… - Biosensors and …, 2021 - Elsevier
Optical biosensors are low-cost, sensitive and portable devices that are poised to
revolutionize the medical industry. Healthcare monitoring has already been transformed by …

Sex differences associated with adverse drug reactions resulting in hospital admissions

LC Hendriksen, PD van der Linden… - Biology of sex …, 2021 - Springer
Background Adverse drug events, including adverse drug reactions (ADRs), are responsible
for approximately 5% of unplanned hospital admissions: a major health concern. Women …

Sex-related differences in drugs with anti-inflammatory properties

A Farkouh, C Baumgärtel, R Gottardi… - Journal of clinical …, 2021 - mdpi.com
There is increasing evidence of sex differences in the action of anti-inflammatory drugs, with
women being at significantly higher risk of adverse effects. Nevertheless, clinicians' …