Pleiotropic effects of alpha-ketoglutarate as a potential anti-ageing agent
MM Bayliak, VI Lushchak - Ageing research reviews, 2021 - Elsevier
An intermediate of tricarboxylic acid cycle alpha-ketoglutarate (AKG) is involved in
pleiotropic metabolic and regulatory pathways in the cell, including energy production …
pleiotropic metabolic and regulatory pathways in the cell, including energy production …
Fructose-mediated AGE-RAGE axis: approaches for mild modulation
H Semchyshyn - Frontiers in Nutrition, 2024 - frontiersin.org
Fructose is a valuable and healthy nutrient when consumed at normal levels (≤ 50 g/day).
However, long-term consumption of excessive fructose and elevated endogenous …
However, long-term consumption of excessive fructose and elevated endogenous …
[HTML][HTML] Neuroprotective potential of hydroethanolic hull extract of Juglans regia L. on isoprenaline induced oxidative damage in brain of Wistar rats
The study was aimed at assessing isoprenaline (ISO) induced oxidative damage in brain of
Wistar rats and its protection by hydroethanolic hull extract of Juglans regia. Administration …
Wistar rats and its protection by hydroethanolic hull extract of Juglans regia. Administration …
Effects of exercise training on behavior and brain function after high dose isoproterenol-induced cardiac damage
K Tóth, T Oroszi, EA van der Zee, C Nyakas… - Scientific Reports, 2021 - nature.com
Acute sympathetic stress can result in cardiac fibrosis, but may also lead to mental
dysfunction. Exercise training after isoproterenol (ISO)-induced acute sympathetic stress …
dysfunction. Exercise training after isoproterenol (ISO)-induced acute sympathetic stress …
Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus
A Faulkner, A Tamiato, W Cathery, A Rampin… - Diabetologia, 2020 - Springer
Aims/hypothesis Treatment of vascular complications of diabetes remains inadequate. We
reported that muscle pericytes (MPs) from limb muscles of vascular patients with diabetes …
reported that muscle pericytes (MPs) from limb muscles of vascular patients with diabetes …
Whole-body vibration as a passive alternative to exercise after myocardial damage in middle-aged female rats: Effects on the heart, the brain, and behavior
K Tóth, T Oroszi, C Nyakas, EA van der Zee… - Frontiers in Aging …, 2023 - frontiersin.org
Background Females with cardiovascular disease seem more vulnerable to develop
concomitant mental problems, such as depression and cognitive decline. Although exercise …
concomitant mental problems, such as depression and cognitive decline. Although exercise …
Protective effects of alpha-ketoglutarate against aluminum toxicity in Drosophila melanogaster
In recent years, Drosophila melanogaster has emerged as a model for studies on aluminum
toxicity. The current study aimed to disclose the mechanisms of aluminum toxicity in D …
toxicity. The current study aimed to disclose the mechanisms of aluminum toxicity in D …
[HTML][HTML] In Silico and In Vivo Studies of β-Sitosterol Nanoparticles as a Potential Therapy for Isoprenaline-Induced Cognitive Impairment in Myocardial Infarction …
PS Tallapalli, YD Reddy, DA Yaraguppi, SP Matangi… - Pharmaceuticals, 2024 - mdpi.com
Objective: This study aimed to compare the effects of β-sitosterol nanoparticles (BETNs) and
β-sitosterol (BET) on cognitive impairment, oxidative stress, and inflammation in a …
β-sitosterol (BET) on cognitive impairment, oxidative stress, and inflammation in a …
Cardioprotective effect of hemin in isoprenaline‐induced myocardial infarction: role of ATP‐sensitive potassium channel and endothelial nitric oxide synthase
MMM Refaie, RA Rifaai, AMA Bayoumi… - Fundamental & …, 2020 - Wiley Online Library
Ischemic heart disease is a common cardiac health problem. Despite the significant
advances in prevention and treatment of this disorder, its incidences and complications are …
advances in prevention and treatment of this disorder, its incidences and complications are …
Ameliorating effect of ketogenic diet on acute status epilepticus: Insights into biochemical and histological changes in rat hippocampus
This study aimed to evaluate the potential neuroprotective effects of ketogenic diet (KD)
against the neuronal disruptions induced by SE in lithium‐pilocarpine rat model of status …
against the neuronal disruptions induced by SE in lithium‐pilocarpine rat model of status …