Lung cancer, renowned for its fast progression and metastatic potency, is rising to become a
leading cause of death globally. It has been long observed that lung cancer is particularly …

Recognizing that the transformative effects of immunotherapy are currently limited to a
minority of patients with cancer, research efforts are increasingly focused on expanding and …

Steroid hormones are lipophilic molecules produced in one cell that can travel great
distances within the body to elicit biological effects in another cell. In the canonical pathway …

Vascular and cardiac valvular calcification was once considered to be a degenerative and
end stage product in aging cardiovascular tissues. Over the past two decades, however, a …

Context Laboratory studies have demonstrated that triclosan (TCS) can cause significant
interstitial collagen accumulation and an increase in trabecular bone. However, little is …

It is well understood that the balance of bone formation and resorption is dependent on both
mechanical and biochemical factors. In addition to cell-secreted cytokines and growth …

Opioids are pivotal therapeutics in the management of escalated chronic pain (moderate–
severe). In the last two decades, the increased prescription rate and the prolonged usage of …

Background: Owing to its multifactorial intricate pathogenesis, combined therapeutic
regimen is considered appropriate for the treatment of osteoporosis. However, a multi-drug …

Icariin (ICA) is a major active ingredient in Herba epimedii, which is commonly used as a
Chinese herbal medicine for the treatment of osteoporosis. Previous studies have revealed …

Background and objective: There is limited information as to the association of several key
bone markers with bone mineral density (BMD) in understudied ethnic groups. This study …