Towards artificial intelligence-enabled extracellular vesicle precision drug delivery
Abstract Extracellular Vesicles (EVs), particularly exosomes, recently exploded into
nanomedicine as an emerging drug delivery approach due to their superior biocompatibility …
nanomedicine as an emerging drug delivery approach due to their superior biocompatibility …
Extracellular vesicles in pancreatic cancer immune escape: emerging roles and mechanisms
C Liu, D He, L Li, S Zhang, L Wang, Z Fan… - Pharmacological …, 2022 - Elsevier
Pancreatic cancer (PC) is the most lethal malignancy worldwide due to its delayed diagnosis
and limited treatment options. Despite great progress in clinical trials of immunotherapies for …
and limited treatment options. Despite great progress in clinical trials of immunotherapies for …
Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy
M Shao, D Lopes, J Lopes, S Yousefiasl… - Matter, 2023 - cell.com
Bio-mimicking principles have recently been proposed for the surface functionalization of
nanoparticles (NPs). Such a strategy is based on camouflaging the NP surface with …
nanoparticles (NPs). Such a strategy is based on camouflaging the NP surface with …
Lipid-based nanovesicular drug delivery systems
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …
Biodelivery of therapeutic extracellular vesicles: should mononuclear phagocytes always be feared?
M Cieślik, K Bryniarski, K Nazimek - Frontiers in Cell and …, 2023 - frontiersin.org
At present, extracellular vesicles (EVs) are considered key candidates for cell-free therapies,
including treatment of allergic and autoimmune diseases. However, their therapeutic …
including treatment of allergic and autoimmune diseases. However, their therapeutic …
Engineered extracellular vesicles as a targeted delivery platform for precision therapy
Y Sun, F Sun, W Xu, H Qian - Tissue Engineering and Regenerative …, 2023 - Springer
Extracellular vesicles (EVs)-based cell-free strategy has shown therapeutic potential in
tissue regeneration. Due to their important roles in intercellular communications and their …
tissue regeneration. Due to their important roles in intercellular communications and their …
Extracellular vesicles: A new diagnostic biomarker and targeted drug in osteosarcoma
X Gao, B Gao, S Li - Frontiers in Immunology, 2022 - frontiersin.org
Osteosarcoma (OS) is a primary bone cancer that is highly prevalent among adolescents
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …
[HTML][HTML] Functions and therapeutic potentials of exosomes in osteosarcoma
J Yue, ZS Chen, XX Xu, S Li - Acta materia medica, 2022 - ncbi.nlm.nih.gov
Osteosarcoma is a primary malignant tumor of the skeleton with the morbidity of 2.5 in 1
million. The regularly on-set is in the epiphysis of the extremities with a high possibility of …
million. The regularly on-set is in the epiphysis of the extremities with a high possibility of …
[HTML][HTML] Cellular nanovesicles for therapeutic immunomodulation: A perspective on engineering strategies and new advances
Cellular nanovesicles which are referred to as cell-derived, nanosized lipid bilayer
structures, have emerged as a promising platform for regulating immune responses. Owing …
structures, have emerged as a promising platform for regulating immune responses. Owing …
Glioblastoma cell-derived exosomes functionalized with peptides as efficient nanocarriers for synergistic chemotherapy of glioblastoma with improved biosafety
Y Zhou, L Wang, L Chen, W Wu, Z Yang, Y Wang… - Nano Research, 2023 - Springer
Glioblastoma (GBM) has been regarded as one of the most deadly and challenging cancers
to treat with extremely poor prognosis. The limited efficacy of current chemotherapies might …
to treat with extremely poor prognosis. The limited efficacy of current chemotherapies might …