Biosensing with dnazymes

EM McConnell, I Cozma, Q Mou, JD Brennan… - Chemical Society …, 2021 - pubs.rsc.org
This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

Metal sensing by DNA

W Zhou, R Saran, J Liu - Chemical reviews, 2017 - ACS Publications
Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

DNAzymes as activity-based sensors for metal ions: recent applications, demonstrated advantages, current challenges, and future directions

RJ Lake, Z Yang, JJ Zhang, Y Lu - Accounts of chemical research, 2019 - ACS Publications
Conspectus Metal ions can be beneficial or toxic depending on their identity, oxidation state,
and concentration. Therefore, the ability to detect and quantify different types of metal ions …

Fluorescent and colorimetric sensors for detection of lead, cadmium, and mercury ions

HN Kim, WX Ren, JS Kim, J Yoon - Chemical Society Reviews, 2012 - pubs.rsc.org
Exposure to even very low levels of lead, cadmium, and mercury ions is known to cause
neurological, reproductive, cardiovascular, and developmental disorders, which are more …

Metal ion sensors based on DNAzymes and related DNA molecules

XB Zhang, RM Kong, Y Lu - Annual review of analytical …, 2011 - annualreviews.org
Metal ion sensors are an important yet challenging field in analytical chemistry. Despite
much effort, only a limited number of metal ion sensors are available for practical use …

Applying CRISPR/Cas system as a signal enhancer for DNAzyme-based lead ion detection

Y Chen, H Wu, S Qian, X Yu, H Chen, J Wu - Analytica Chimica Acta, 2022 - Elsevier
Heavy metal lead accumulation in the environment pollutes the ecology systems and further
threatens the human health. It is necessary to develop a sensitive method to detect it. Here …

Biochemical and biophysical understanding of metal ion selectivity of DNAzymes

K Hwang, P Hosseinzadeh, Y Lu - Inorganica chimica acta, 2016 - Elsevier
This review summarizes research on the metal-binding properties of catalytic DNAzymes,
towards the goal of understanding the structural properties leading to metal ion specificity …

Functional nucleic acid-based sensors for heavy metal ion assays

G Zhu, C Zhang - Analyst, 2014 - pubs.rsc.org
Heavy metal contaminants such as lead ions (Pb2+), mercury ions (Hg2+) and silver ions
(Ag+) can cause significant harm to humans and generate enduring bioaccumulation in …

Solid-phase colorimetric sensor based on gold nanoparticle-loaded polymer brushes: lead detection as a case study

AR Ferhan, L Guo, X Zhou, P Chen, S Hong… - Analytical …, 2013 - ACS Publications
We introduce a novel solid-phase colorimetric sensor facilely fabricated by loading
unmodified gold nanoparticles into poly (oligo (ethylene glycol) methacrylate)(POEGMA) …

Recent advances on functional nucleic-acid biosensors

X Yu, S Zhang, W Guo, B Li, Y Yang, B Xie, K Li… - Sensors, 2021 - mdpi.com
In the past few decades, biosensors have been gradually developed for the rapid detection
and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have …