Accelerating Oral Wound Healing Using Bilayer Biomaterial Delivery of FTY720 Immunotherapy

AI Toma, D Shah, D Roth, JO Piña… - Advanced …, 2024 - Wiley Online Library
Orofacial clefts are the most common congenital craniofacial anomaly. Adverse healing
following cleft palate repair can lead to oronasal fistula (ONF), a persistent connection …

Inclusivity and Equity in Biotechnology: Insights from the AfroBiotech Conferences

KA Haynes - GEN Biotechnology, 2024 - liebertpub.com
The international AfroBiotech conference series, launched in 2019 in Atlanta, GA, USA, is an
emerging platform to foster innovation, promote inclusivity, and highlight the contributions of …

Intersection of Immunity, Metabolism, and Muscle Regeneration in an Autoimmune‐Prone MRL Mouse Model

TB Ngo, A Josyula, S DeStefano, D Fertil… - Advanced …, 2024 - Wiley Online Library
Due to the limited capacity of mammals to regenerate complex tissues, researchers have
worked to understand the mechanisms of tissue regeneration in organisms that maintain that …

Biomaterial-Based Regenerative Strategies for Volumetric Muscle Loss: Challenges and Solutions

CW Cai, JA Grey, D Hubmacher… - Advances in Wound Care, 2024 - liebertpub.com
Significance: Volumetric muscle loss (VML) is caused by the loss of significant amounts of
skeletal muscle tissue. VML cannot be repaired by intrinsic regenerative processes …

[HTML][HTML] Ectopic adipogenesis in response to injury and material implantation in an autoimmune mouse model

TB Ngo, A Josyula, S DeStefano, D Fertil, M Faust… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Due to the limited capacity of mammals to regenerate complex tissues, researchers have
worked to understand the mechanisms of tissue regeneration in organisms that maintain that …

[HTML][HTML] Effects of injury size on local and systemic immune cell dynamics in volumetric muscle loss

R Whitaker, S Sung, T Tylek, G Risser, E O'Brien… - bioRxiv, 2024 - ncbi.nlm.nih.gov
We took a systems approach to the analysis of macrophage phenotype in regenerative and
fibrotic volumetric muscle loss outcomes in mice together with analysis of systemic …

Improving Functional Muscle Regeneration in Volumetric Muscle Loss Injuries by Shifting the Balance of Inflammatory and Pro-Resolving Lipid Mediators

TC Turner, FS Pittman, H Zhang, LA Hymel, T Zheng… - bioRxiv, 2024 - biorxiv.org
Severe tissue loss resulting from extremity trauma, such as volumetric muscle loss (VML),
poses significant clinical challenges for both general and military populations. VML disrupts …

Harnessing Bilayer Biomaterial Delivery of FTY720 as an Immunotherapy to Accelerate Oral Wound Healing

AI Toma, D Shah, D Roth, J Oliver Pina, LA Hymel… - bioRxiv, 2023 - biorxiv.org
Orofacial clefts are the most common craniofacial congenital anomaly. Following cleft palate
repair, up to 60% of surgeries have wound healing complications leading to oronasal fistula …

Understanding and Tuning the Immune Response in Volumetric Muscle Loss (VML) Injury

RC Whitaker - 2024 - search.proquest.com
Abstract Volumetric Muscle Loss (VML) is a debilitating condition characterized by the
sudden loss of 20% or more of muscle mass, leading to tissue impairment. These types of …