Epilepsy is one of the most common neurological chronic disorders, with an estimated
prevalence of 0. 5–1%. Currently, treatment options for epilepsy are predominantly based on …

Cognitive neuroscience studies in humans have enabled decades of impactful discoveries
but have primarily been limited to recording the brain activity of immobile participants in a …

Epileptic seizures vary greatly in clinical phenomenology and can markedly affect the
patient's quality of life. As therapeutic interventions focus on reduction or elimination of …

Brain–machine interfaces (BMIs) create closed-loop control systems that interact with the
brain by recording and modulating neural activity and aim to restore lost function, most …

Controlled clinical trials in adults with medically intractable focal seizures treated with the
RNS® System demonstrate that closed-loop responsive neurostimulation to the seizure …

Neuromodulation is a key therapeutic tool for clinicians managing patients with drug‐
resistant epilepsy. Multiple devices are available with long‐term follow‐up and real‐world …

Surgical treatment for epilepsy remains underutilized, in part because of persistent
misconceptions. Rather than promote referral for surgery, it would be more appropriate to …

Abstract Objective The RNS System is a direct brain‐responsive neurostimulation system
that is US Food and Drug Administration–approved for adults with medically intractable focal …

Background A seizure prediction system can detect seizures prior to their occurrence and
allow clinicians to provide timely treatment for patients with epilepsy. Research on seizure …

Cognitive functions are increasingly understood to involve coordinated activity patterns
between multiple brain regions, and their disruption by neuropsychiatric disorders is …