[HTML][HTML] PaccMannRL: De novo generation of hit-like anticancer molecules from transcriptomic data via reinforcement learning

J Born, M Manica, A Oskooei, J Cadow, G Markert… - Iscience, 2021 - cell.com
With the advent of deep generative models in computational chemistry, in-silico drug design
is undergoing an unprecedented transformation. Although deep learning approaches have …

Methods of imaging and treatment

EC Unger, Y Wu - US Patent 7,329,402, 2008 - Google Patents
US7329402B2 - Methods of imaging and treatment - Google Patents US7329402B2 -
Methods of imaging and treatment - Google Patents Methods of imaging and treatment …

Multifunctional Nanoparticle Conjugates And Their Use

S Nie, YK Lee, G Kim - US Patent App. 11/664,886, 2009 - Google Patents
(86). PCT No.: PCT/USOS/36222(57) ABSTRACT Disclosed herein are conjugates
comprising a nanocarrier, a therapeutic agent or imaging agent and a targeting agent. Also …

Pyrvinium for the Treatment of Cancer

E Lee, L Lee, C Thorne, E Tahinci… - US Patent App. 12 …, 2009 - Google Patents
The present invention concerns a pyrvinium compound or an analog thereof for the
treatment of cancers. This compound inhibits Wnt activity in the cells of cancers such as …

High frequency ultrasound imaging using contrast agents

DE Goertz, FS Foster - US Patent 8,708,909, 2014 - Google Patents
US PATENT DOCUMENTS compositions disclosed herein. Specifically provided are
methods for producing an ultrasound image comprising: administering contrast agent to a …

Method and system for providing configurable features for graphical user interfaces for electronic trading

AJ Badenhorst, JC Downs - US Patent 7,627,517, 2009 - Google Patents
A method and system for providing configurable features for a multi-windowed graphical
user interface (GUI) for electronic trading. The configurable features include, but are not …

Therapeutic delivery systems

EC Unger, TA Fritz, T Matsunaga… - US Patent …, 2006 - Google Patents
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delivery systems - Google Patents Therapeutic delivery systems Download PDF Info Publication …

Method and system for electronic trading via a yield curve

RJ Mackey Jr, EJ Harvey III - US Patent 7,734,533, 2010 - Google Patents
7,483,850 B1 1/2009 Fishbain et al. 2003, OO88495 A1 5.2003 Gilbert et al. 7.483, 855 B1
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Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics

R Lyon, P Burke, J Hunter - US Patent 11,103,593, 2021 - Google Patents
2021-04-22 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
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Gas microsphere liposome composites for ultrasound imaging and ultrasound stimulated drug release

A Carpenter, G Slack - US Patent App. 09/931,317, 2003 - Google Patents
Correspondence Address: Formulations comprising a gas microSphere lipoSome com
STEPHEN B. DAVIS posite Suspended in a medium, wherein the gas microSphere …