Dexamethasone for inpatients with COVID-19 in a national cohort
Importance Limited effective therapeutics are available to hospitalized patients with COVID-
19. Clinical trials and observational studies have shown varying effects of systemic …
19. Clinical trials and observational studies have shown varying effects of systemic …
Drug repurposing and observational studies: the case of antivirals for the treatment of COVID-19
MA Hernán, J Del Amo - Annals of Internal Medicine, 2023 - acpjournals.org
Remdesivir and molnupiravir were the only 2 repurposed antivirals that were approved for
emergency use during the COVID-19 pandemic. Both drugs received their emergency use …
emergency use during the COVID-19 pandemic. Both drugs received their emergency use …
Clinical antiviral efficacy of remdesivir in coronavirus disease 2019: an open-label, randomized controlled adaptive platform trial (PLATCOV)
P Jittamala, WHK Schilling, JA Watson… - The Journal of …, 2023 - academic.oup.com
Background Uncertainty over the therapeutic benefit of parenteral remdesivir in coronavirus
disease 2019 (COVID-19) has resulted in varying treatment guidelines. Methods In a …
disease 2019 (COVID-19) has resulted in varying treatment guidelines. Methods In a …
Clinical characteristics and implications of bradycardia in COVID-19 patients treated with remdesivir: a single-center retrospective cohort study
A Schreiber, JS Bauzon, K Batra, S Mohammed… - Clinical Drug …, 2022 - Springer
Abstract Background and Objectives Remdesivir is an antiviral drug used to treat
coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac effect profile …
coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac effect profile …
Viral Pneumonia: From Influenza to COVID-19
C Cilloniz, G Dy-Agra… - … in Respiratory and …, 2024 - thieme-connect.com
Respiratory viruses are increasingly recognized as a cause of community-acquired
pneumonia (CAP). The implementation of new diagnostic technologies has facilitated their …
pneumonia (CAP). The implementation of new diagnostic technologies has facilitated their …
Remdesivir in patients with severe kidney dysfunction: a secondary analysis of the CATCO randomized trial
Remdesivir is a broad-spectrum antiviral that reduces hospitalization and may decrease
mortality among noncritically ill inpatients with COVID-19. 1, 2 Remdesivir is not …
mortality among noncritically ill inpatients with COVID-19. 1, 2 Remdesivir is not …
Clinical evolution and mortality of critically ill patients with SARS-CoV-2 pneumonia treated with remdesivir in an adult intensive care unit of Paraguay
J Figueredo, LF Lopez, BF Leguizamon… - BMC Infectious …, 2024 - Springer
Background The health crisis due to Covid-19 led to the search for therapeutics that could
improve the evolution of the disease. Remdesivir, an antiviral that interferes with viral …
improve the evolution of the disease. Remdesivir, an antiviral that interferes with viral …
Multistudy research operations in the ICU: an interprofessional pandemic-informed approach
OBJECTIVES: Proliferation of COVID-19 research underscored the need for improved
awareness among investigators, research staff and bedside clinicians of the operational …
awareness among investigators, research staff and bedside clinicians of the operational …
[HTML][HTML] The effects of remdesivir on mortality and the requirement for mechanical ventilation in patients with COVID-19: a systematic review stratified by disease …
S Ryoo, M Choi, SY Yu, YK Yoon, K Huh… - The Korean Journal of …, 2024 - ncbi.nlm.nih.gov
Methods We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials,
and other data resources to find RCTs published prior to April 10, 2023. The selection of …
and other data resources to find RCTs published prior to April 10, 2023. The selection of …
[HTML][HTML] Time required to initiate a clinical trial in Canada at the onset of the COVID-19 pandemic: an observational research-in-motion study
K Teo, RA Fowler, NKJ Adhikari, A Rishu… - … Open Access Journal, 2023 - cmajopen.ca
Background: Randomized controlled trials (RCTs) provide essential evidence to inform
practice, but the many necessary steps result in lengthy times to initiation, which is …
practice, but the many necessary steps result in lengthy times to initiation, which is …