Kernel machine SNP set analysis finds the association of BUD13, ZPR1, and APOA5 variants with metabolic syndrome in Tehran Cardio-metabolic Genetics Study

S Masjoudi, B Sedaghati-Khayat, NJ Givi… - Scientific Reports, 2021 - nature.com
Metabolic syndrome (MetS) is one of the most important risk factors for cardiovascular
disease. The 11p23. 3 chromosomal region plays a potential role in the pathogenesis of …

Sex-specific association of FABP2 polymorphisms with the risk of obesity in the Tehran Cardio-Metabolic Genetic Study (TCGS)

L Najd-Hassan-Bonab, NJ Givi, M Moazzam-Jazi… - Gene, 2023 - Elsevier
FABP2 is one of the key genes involved in obesity development across different populations.
However, there is no comprehensive report about the FABP2 contribution to obesity …

Integrating Multimorbidity into a Whole-Body Understanding of Disease Using Spatial Genomics

S Gokuladhas, RE Zaied, W Schierding… - … Genomic Architecture in …, 2022 - Springer
Multimorbidity is characterized by multidimensional complexity emerging from interactions
between multiple diseases across levels of biological (including genetic) and environmental …