Type 2 diabetes

E Ahmad, S Lim, R Lamptey, DR Webb, MJ Davies - The Lancet, 2022 - thelancet.com
Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes
worldwide. The number affected is increasing rapidly with alarming trends in children and …

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Randomized trial comparing the effects of gliclazide, liraglutide, and metformin on diabetes with non‐alcoholic fatty liver disease: 比较格列齐特, 利拉鲁肽和二甲双胍对 …

W Feng, C Gao, Y Bi, M Wu, P Li, S Shen… - Journal of …, 2017 - Wiley Online Library
背景本研究旨在比较格列齐特, 利拉鲁肽和二甲双胍对2 型糖尿病合并非酒精性脂肪肝患者的
影响. 方法87 名患者随机接受为期24 周的格列齐特, 利拉鲁肽或二甲双胍治疗 …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

American Association of Clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and …

K Cusi, S Isaacs, D Barb, R Basu, S Caprio… - Endocrine Practice, 2022 - Elsevier
Objective To provide evidence-based recommendations regarding the diagnosis and
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …

Challenges and opportunities in NASH drug development

SA Harrison, AM Allen, J Dubourg, M Noureddin… - Nature medicine, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

M Chakhtoura, R Haber, M Ghezzawi, C Rhayem… - …, 2023 - thelancet.com
Obesity is an epidemic and a public health threat. Medical weight management remains one
of the options for the treatment of excess weight and recent advances have revolutionized …

[HTML][HTML] 4. Comprehensive medical evaluation and assessment of comorbidities: Standards of Care in Diabetes—2023

NA ElSayed, G Aleppo, VR Aroda, RR Bannuru… - Diabetes …, 2023 - ncbi.nlm.nih.gov
The American Diabetes Association (ADA)“Standards of Care in Diabetes” includes the
ADA's current clinical practice recommendations and is intended to provide the components …

A global view of the interplay between non-alcoholic fatty liver disease and diabetes

N Stefan, K Cusi - The lancet Diabetes & endocrinology, 2022 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) has become an epidemic, much like other non-
communicable diseases (NCDs), such as cancer, obesity, diabetes, and cardiovascular …

Semaglutide 2· 4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial

R Loomba, MF Abdelmalek, MJ Armstrong… - The Lancet …, 2023 - thelancet.com
Background Patients with non-alcoholic steatohepatitis (NASH)-related cirrhosis are at high
risk of liver-related and all-cause morbidity and mortality. We investigated the efficacy and …