Engineered living materials for sustainability
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …
materials, namely engineered living materials (ELMs), which are composed of living matter …
Decorated bacteria and the application in drug delivery
F Wu, J Liu - Advanced Drug Delivery Reviews, 2022 - Elsevier
The use of living bacteria either as therapeutic agents or drug carriers has shown great
potential in treating a multitude of intractable diseases. However, cells are often fragile to …
potential in treating a multitude of intractable diseases. However, cells are often fragile to …
A single-cell nanocoating of probiotics for enhanced amelioration of antibiotic-associated diarrhea
The gut microbiota represents a large community of microorganisms that play an important
role in immune regulation and maintenance of homeostasis. Living bacteria receive …
role in immune regulation and maintenance of homeostasis. Living bacteria receive …
Surface-modified bacteria: synthesis, functionalization and biomedical applications
S Lin, F Wu, Y Zhang, H Chen, H Guo… - Chemical Society …, 2023 - pubs.rsc.org
The past decade has witnessed a great leap forward in bacteria-based living agents,
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …
including imageable probes, diagnostic reagents, and therapeutics, by virtue of their unique …
Biointerface mineralization generates ultraresistant gut microbes as oral biotherapeutics
Z Geng, X Wang, F Wu, Z Cao, J Liu - Science advances, 2023 - science.org
Despite the fact that oral microecologics are effective in modulating the gut microbiome, they
always suffer from multiple insults during the journey from manufacture to arrival at the …
always suffer from multiple insults during the journey from manufacture to arrival at the …
Encoding bacterial colonization and therapeutic modality by wrapping with an adhesive drug-loadable nanocoating
H Luo, F Wu, X Wang, S Lin, M Zhang, Z Cao, J Liu - Materials Today, 2023 - Elsevier
Microbial therapy has shown remarkable clinical success. However, insufficient colonization
of transplanted microbes at the location of interest and the complexity of mechanisms and …
of transplanted microbes at the location of interest and the complexity of mechanisms and …
Bioinspired oral delivery devices
Oral administration is a widespread and convenient drug delivery approach. However, oral
delivery can be affected by the complex digestive tract environment, including irregular …
delivery can be affected by the complex digestive tract environment, including irregular …
Inorganic nanosheet-shielded probiotics: a self-adaptable oral delivery system for intestinal disease treatment
YX Zhu, Y You, Z Chen, D Xu, W Yue, X Ma, J Jiang… - Nano Letters, 2023 - ACS Publications
The oral delivery of probiotics is commonly adopted for intestinal disease treatments in
clinical settings; however, the probiotics suffer from a strong acidic attack in the gastric area …
clinical settings; however, the probiotics suffer from a strong acidic attack in the gastric area …
[HTML][HTML] pH-responsive hybrid platelet membrane-coated nanobomb with deep tumor penetration ability and enhanced cancer thermal/chemodynamic therapy
H Yang, Y Ding, Z Tong, X Qian, H Xu, F Lin… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Despite their outstanding properties in high surface-to-volume ratio and deep
penetration, the application of ultrasmall nanoparticles for tumor theranostics remains limited …
penetration, the application of ultrasmall nanoparticles for tumor theranostics remains limited …
Cell‐in‐Catalytic‐Shell Nanoarchitectonics: Catalytic Empowerment of Individual Living Cells by Single‐Cell Nanoencapsulation
Cell‐in‐shell biohybrid structures, synthesized by encapsulating individual living cells with
exogenous materials, have emerged as exciting functional entities for engineered living …
exogenous materials, have emerged as exciting functional entities for engineered living …