Human endogenous retroviruses (HERVs) are relics of ancient infections accounting for
about the 8% of our genome. Despite their persistence in human DNA led to the …

Multiple sclerosis (MS) is an immune inflammatory disease, where the underlying etiological
cause remains elusive. Multiple triggering factors have been suggested, including …

Objective Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of
motor neurons, of unknown etiology. Previous studies showed reverse transcriptase in …

Multiple sclerosis-associated retroviral element (MSRV) is a retroviral element, the
sequence of which served to define the W family of human endogenous retroviruses. MSRV …

Roles for viral infections and aberrant immune responses in driving localized
neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of …

Background Proposed co-factors triggering the pathogenesis of multiple sclerosis (MS) are
the Epstein Barr virus (EBV), and the potentially neuropathogenic MSRV (MS-associated …

Genetic and environmental factors jointly determine the susceptibility to develop Multiple
Sclerosis (MS). Collaborative efforts during the past years achieved substantial progress in …

Multiple sclerosis (MS)-associated retrovirus (MSRV)/HERV-W (human endogenous
retrovirus W) and Human herpesvirus 6 (HHV-6) are the two most studied (and discussed) …

Mammalian genomes contain a heavy load (42% in humans) of retroelements, which are
mobile sequences requiring reverse transcription for their replicative transposition. A …

Retroviruses are an important group of pathogens that cause a variety of diseases in
humans and animals. Four human retroviruses are currently known, including human …