Biomineralization is the process by which organisms form mineralized tissues with
hierarchical structures and excellent properties, including the bones and teeth in …

Mature tooth enamel is acellular and does not regenerate itself. Developing technologies
that rebuild tooth enamel and preserve tooth structure is therefore of great interest …

Extracellular matrix proteins play crucial roles in the formation of mineralized tissues like
bone and teeth via multifunctional mechanisms. In tooth enamel, ameloblastin (Ambn) is one …

Transforming growth factor-β1 (TGF-β1) is present in porcine enamel extracts and is critical
for proper mineralization of tooth enamel. Here, we show that the mRNA of latent TGF-β1 is …

The enamel matrix protein Ameloblastin (Ambn) has critical physiological functions,
including regulation of mineral formation, cell differentiation, and cell–matrix adhesion. We …

Hypomineralized enamel may be found in connection with the condition molar incisor
hypomineralization (MIH), which has a prevalence of around 15% in most parts of the world …

Ameloblastin (Ambn), the most abundant non-amelogenin enamel protein, is intrinsically
disordered and has the potential to interact with other enamel proteins and with cell …

Biomineralization is the matrix-directed calcification of tissue in living organisms. The
deposition of different polymorphs of calcium phosphate or calcium carbonate is a highly …

We have recently reported that the extracellular enamel protein amelogenin has affinity to
interact with phospholipids and proposed that such interactions may play key roles in …

Interactions between enamel matrix proteins are important for enamel biomineralization. In
recent in situ studies, we showed that the N-terminal proteolytic product of ameloblastin co …