Cyclic AMP (cAMP) is found in a variety of prokaryotes including both eubacteria and
archaebacteria. cAMP plays a role in regulating gene expression, not only for the classic …

Structural studies of DNA-binding proteins and their complexes with DNA have proceeded at
an accelerating pace in recent years due to important technical advances in molecular …

Allosteric regulation is used as a very efficient mechanism to control protein activity in most
biological processes, including signal transduction, metabolism, catalysis and gene …

Novel DNA-binding proteins, especially repressors of gene expression, are obtained by
variegation of genes encoding known binding protein and selection for proteins binding the …

The cyclic AMP receptor protein (CRP) of Escherichia coli is a dimer made up of identical
subunits. Each CRP subunit contains a cyclic nucleotide binding pocket and the CRP dimer …

The structure of a dimer of the Escherichia coli catabolite gene activator protein has been
refined at 2.5 Å resolution to a crystallographic R-factor of 20.7% starting with coordinates …

1990-09-25 Assigned to PROTEIN ENGINEERING CORPORATION reassignment PROTEIN
ENGINEERING CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST. Assignors …

The cAMP-mediated allosteric transition in the catabolite activator protein (CAP; also known
as the cAMP receptor protein, CRP) is a textbook example of modulation of DNA-binding …

CooA is a homodimeric transcription factor that belongs to the catabolite activator protein
(CAP) family. Binding of CO to the heme groups of CooA leads to the transcription of genes …

After an allosteric transition produced by the binding of cyclic AMP (cAMP), the Escherichia
coli catabolite gene activator protein (CAP) binds DNA specifically and activates …