Cytokine expression in periodontal health and disease

H Okada, S Murakami - Critical Reviews in Oral Biology & …, 1998 - journals.sagepub.com
Soluble proteins that serve as mediators of cell function and are produced by various cell
types, such as structural and inflammatory cells, are collectively called cytokines. Several …

The pathogenesis of atherosclerosis: atherogenesis and inflammation

JM Munro, RS Cotran - Pathology Reviews· 1989, 1989 - Springer
Atherosclerosis and its complications, such as myocardial infarction, stroke, and peripheral
vascular disease, remain major causes of morbidity and mortality in the Western World; …

Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms.

GF Pierce, TA Mustoe, J Lingelbach… - The Journal of cell …, 1989 - rupress.org
Platelet-derived growth factor (PDGF) and transforming growth factor-beta (TGF-beta)
markedly potentiate tissue repair in vivo. In the present experiments, both in vitro and in vivo …

Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation.

N Khalil, O Bereznay, M Sporn… - The Journal of …, 1989 - rupress.org
A rat model of bleomycin-induced pulmonary inflammation and fibrosis was used to examine
the relationship between collagen synthesis and transforming growth factor beta (TGF-beta) …

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

EJ Battegay, EW Raines, RA Seifert, DF Bowen-Pope… - Cell, 1990 - cell.com
Transforming growth factor-p (TGF-p) acts as a growth inhibitor, yet it can stimulate
proliferation; l-2 fg/cell of TGF-pl elicits maximal proliferation of dense and sparse cultured …

A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies

JS Forrester, M Fishbein, R Helfant, J Fagin - Journal of the American …, 1991 - Elsevier
Angioplasty causes substantial injury to the coronary artery intima and media that is
unrecognizable by angiography. On the basis of a substantial body of research in oncology …

The Transforming Growth Factor-βs

AB Roberts, MB Sporn - Peptide growth factors and their receptors I, 1990 - Springer
Following the initial purification and characterization of transforming growth factor-p (TGF-p)
as a homodimeric, 25-kDa peptide (FROLIK et al. 1983; As-SOlAN et al. 1983; ROBERTS et …

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only.

E Brogi, T Wu, A Namiki, JM Isner - Circulation, 1994 - Am Heart Assoc
BACKGROUND Hypoxia and indirect angiogenic factors may stimulate angiogenesis via
induction of endothelial cell mitogen (s). To evaluate this hypothesis, we investigated …

Production of transforming growth factor beta 1 during repair of arterial injury.

MW Majesky, V Lindner, DR Twardzik… - The Journal of …, 1991 - Am Soc Clin Investig
Repair of arterial injury produced by balloon angioplasty leads to the formation of a
neointima and a narrowing of the vascular lumen. In this study, we examined the possibility …

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial …

S Okuda, LR Languino, E Ruoslahti… - The Journal of clinical …, 1990 - Am Soc Clin Investig
Glomerular accumulation of extracellular matrix is a prominent feature of progressive
glomerulonephritis. Previously, we have shown that transforming growth factor-beta (TGF …