Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterized by multiple
pathologies. The progression of dementia with NAFLD may be affected by various risk …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

G protein-gated inwardly rectifying potassium channels (Kir3/GirK) are important for
maintaining resting membrane potential, cell excitability and inhibitory neurotransmission …

G protein-gated inwardly rectifying K+ (GIRK/Kir3) channels exert a critical inhibitory
influence on neurons. Neuronal GIRK channels mediate the G protein-dependent …

The G-protein-gated inwardly rectifying potassium (Kir3/GIRK) channel is the effector of
many G-protein-coupled receptors (GPCRs). Its dysfunction has been linked to the …

Synaptic plasticity is a cellular process involved in learning and memory by which specific
patterns of neural activity adapt the synaptic strength and efficacy of the synaptic …

For the past two decades several scholarly reviews have appeared on the inwardly rectifying
potassium (Kir) channels. We would like to highlight two efforts in particular, which have …

Abstract Serotonin (5-HT) is one of the fundamental neurotransmitters that contribute to the
information essential for an organism's normal, physiological function. Serotonin acts …