Nanocarriers for cancer-targeted drug delivery

P Kumari, B Ghosh, S Biswas - Journal of drug targeting, 2016 - Taylor & Francis
Nanoparticles as drug delivery system have received much attention in recent years,
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …

Nucleic acid therapeutics using polyplexes: a journey of 50 years (and beyond)

U Lächelt, E Wagner - Chemical reviews, 2015 - ACS Publications
Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

Dendrimer as nanocarrier for drug delivery

P Kesharwani, K Jain, NK Jain - Progress in Polymer Science, 2014 - Elsevier
Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …

Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery

AP Pandey, KK Sawant - Materials Science and Engineering: C, 2016 - Elsevier
Polyethylenimine (PEI) has recently been widely studied for the design of nucleic acid
delivery vehicles. Gene delivery using PEI involves condensation of DNA into compact …

Nonviral vectors for gene delivery

MA Mintzer, EE Simanek - Chemical reviews, 2009 - ACS Publications
Gene therapy has gained significant attention over the past two decades as a potential
method for treating genetic disorders such as severe combined immunodeficiency, 1 cystic …

Thermo-and pH-responsive polymers in drug delivery

D Schmaljohann - Advanced drug delivery reviews, 2006 - Elsevier
Stimuli-responsive polymers show a sharp change in properties upon a small or modest
change in environmental condition, eg temperature, light, salt concentration or pH. This …

Dendrimers in biomedical applications—reflections on the field

S Svenson, DA Tomalia - Advanced drug delivery reviews, 2012 - Elsevier
The formation of particulate systems with well-defined sizes and shapes is of eminent
interest in certain medical applications such as drug delivery, gene transfection, and …

[HTML][HTML] PAMAM dendrimers as promising nanocarriers for RNAi therapeutics

P Kesharwani, S Banerjee, U Gupta, MCIM Amin… - Materials Today, 2015 - Elsevier
Therapeutics based on RNA interference mechanisms are highly promising for the
management of several diseases including multi-drug resistant cancers. However, effective …

Michael addition reactions in macromolecular design for emerging technologies

BD Mather, K Viswanathan, KM Miller… - Progress in Polymer …, 2006 - Elsevier
The Michael addition reaction is a versatile synthetic methodology for the efficient coupling
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …

Syntheses and structures of magnetic nanodendrimers and their catalytic application in organic synthesis

F Kalantari, S Rezayati, A Ramazani… - Applied …, 2023 - Wiley Online Library
Magnetic nanoparticles have been proved as a tremendously powerful synthetic tool to
achieve a milder process for the organic transformations and also suggested many …