White matter hyperintensities (WMHs) are frequently seen on brain magnetic resonance
imaging scans of older people. Usually interpreted clinically as a surrogate for cerebral …

Abstract Purpose of Review Nutrition is known to modulate the immune system and may
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …

Few studies have focused on the connection between glymphatic dysfunction and cerebral
small vessel disease (CSVD), partially due to the lack of non-invasive methods to measure …

Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

People with type 2 diabetes mellitus (T2DM) are at increased risk of mild cognitive
impairment and dementia. Systemic inflammation has been proposed as a common risk …

Importance Older adults with lower intake and tissue levels of long-chain ω-3
polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA; 20: 5) and …

Small vessel disease (SVD) refers to conditions where damage to arterioles and capillaries
is predominant, leading to reduced, or interrupted perfusion of the affected organ. Data …

Lipoprotein-associated phospholipase A2 (Lp-PLA2) and superoxide dismutase (SOD) are
linked to regulating vascular/neuro-inflammation and stroke. Using a retrospective design …

Background Studies suggest a role of the innate immune system, including the activity of
neutrophils, in neurodegeneration related to Alzheimer's disease (AD), but prospective …

White matter hyperintensities (WMHs) of presumed vascular origin are one of the most
important neuroimaging markers of cerebral small vessel disease (CSVD), which are closely …