The aim of engineering of biomaterials is to fabricate implantable biocompatible scaffold that
would accelerate regeneration of the tissue and ideally protect the wound against biodevice …

How microgravity affects the biology of human cells and the formation of 3D cell cultures in
real and simulated microgravity (rand sµg) is currently a hot topic in biomedicine. In rand …

MicroRNAs (miRNAs) interfere with the translation of specific target mRNAs and are thought
to thereby regulate many cellular processes. However, the role of miRNAs in osteoblast …

Abstract 3D printing and ultrasound techniques are showing great promise in the evolution
of human musculoskeletal tissue repair and regeneration medicine. The uniqueness of the …

Mesenchymal stem cells have contributed to the continuous progress of tissue engineering
and regenerative medicine. Adiposederived stem cells (ADSC) possess many advantages …

Microgravity induces observed bone loss in space flight and reduced osteogenesis of bone
mesenchymal stem cells (BMSCs) partly contributes to this phenomenon. Abnormal …

Treatment of bone defects remains a challenge in the clinic. Artificial bone grafts are the
most promising alternative to autologous bone grafting. However, one of the limiting factors …

In vitro manipulation of human stem cells is a critical process in regenerative medicine and
cellular therapies. Strategies and methods to maintain stem cells and direct them into …

In the past decades, bone tissue engineering developed and exploited many typologies of
bioreactors, which, besides providing proper culture conditions, aimed at integrating those …

Background Low-intensity pulsed ultrasound (LIPUS) is a mechanical stimulus that plays a
key role in regulating the differentiation of bone marrow mesenchymal stem cells (BMSCs) …