The role of microRNA as clinical biomarkers for breast cancer surgery and treatment

MG Davey, M Davies, AJ Lowery, N Miller… - International Journal of …, 2021 - mdpi.com
Breast cancer is the most common cancer diagnosed in women. In recent times, survival
outcomes have improved dramatically in accordance with our enhanced understanding of …

Single-cell transcriptome analysis highlights a role for neutrophils and inflammatory macrophages in the pathogenesis of severe COVID-19

H Shaath, R Vishnubalaji, E Elkord, NM Alajez - Cells, 2020 - mdpi.com
Cumulative data link cytokine storms with coronavirus disease 2019 (COVID-19) severity.
The precise identification of immune cell subsets in bronchoalveolar lavage (BAL) and their …

MicroRNAs in molecular classification and pathogenesis of breast tumors

V Richard, MG Davey, H Annuk, N Miller, RM Dwyer… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is an ideal model of a heterogeneous disease that is
triggered by genetic changes in the normal mammary epithelial cells and manifest as …

Epigenetic regulation of triple negative breast cancer (TNBC) by TGF-β signaling

R Vishnubalaji, NM Alajez - Scientific Reports, 2021 - nature.com
TGFβ signaling plays crucial role during development and cancer, however the role for
TGFβ signaling in regulating the noncoding part of the human genome in triple negative …

Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks

R Elango, S Rashid, R Vishnubalaji, R Al-Sarraf… - Cell Death & …, 2023 - nature.com
Previous studies have suggested that breast cancer (BC) from the Middle East and North
Africa (MENA) is presented at younger age with advanced tumor stage, indicating …

Contribution of miRNAs in the Pathogenesis of Breast Cancer

S Ghafouri-Fard, A Khanbabapour Sasi, A Abak… - Frontiers in …, 2021 - frontiersin.org
Breast cancer is the most frequently diagnosed cancer among females. Gene expression
profiling methods have shown the deregulation of several genes in breast cancer samples …

MiR-150-5p overexpression in triple-negative breast cancer contributes to the in vitro aggressiveness of this breast cancer subtype

BM Sugita, Y Rodriguez, AS Fonseca, E Nunes Souza… - Cancers, 2022 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is a clinically aggressive type of
breast cancer. MicroRNAs (miRNAs) are small molecules that regulate the expression of …

Assessing the Role of MicroRNAs in Predicting Breast Cancer Recurrence—A Systematic Review

L Bouz Mkabaah, MG Davey, JC Lennon… - International Journal of …, 2023 - mdpi.com
Identifying patients likely to develop breast cancer recurrence remains a challenge. Thus,
the discovery of biomarkers capable of diagnosing recurrence is of the utmost importance …

Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel

R Elango, R Vishnubalaji, H Shaath… - … Therapy-Methods & …, 2021 - cell.com
Triple-negative breast cancer (TNBC) patients exhibit variable responses to chemotherapy,
suggesting an underlying molecular heterogeneity. In the current study, we analyzed …

Prognostic value of 12 m7G methylation-related miRNA markers and their correlation with immune infiltration in breast cancer

W Zhang, S Zhang, Z Wang - Frontiers in oncology, 2022 - frontiersin.org
RNA guanine-7 methyltransferase (RNMT), in complex with FAM103A1, plays an important
role in tumorigenesis and development. The aim of this study was to establish a prognostic …